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Impedance based devices and methods for use in assays

  • US 20050112544A1
  • Filed: 11/10/2003
  • Published: 05/26/2005
  • Est. Priority Date: 12/20/2002
  • Status: Active Grant
First Claim
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1. A device for detecting cells or molecules on an electrode surface through measurement of impedance changes resulting from attachment or binding of said cells or molecules to said electrode surface, which device comprises:

  • a non-conductive substrate having two opposing ends along a longitudinal axis;

    a plurality of electrode arrays positioned on said substrate, wherein each electrode array comprises at least two electrodes, and further wherein each electrode is separated from at least one adjacent electrode by an area of non-conductive material, said electrode having a width at its widest point of more than about 1.5 and less than about 10 times the width of said area of non-conductive material; and

    electrically conductive traces extending substantially longitudinally to one of said two opposing ends of said substrate, and further wherein each trace is in electrical communication with at least one of said electrode arrays.

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