×

Microarray hybridization device

  • US 20050112589A1
  • Filed: 11/24/2003
  • Published: 05/26/2005
  • Est. Priority Date: 11/24/2003
  • Status: Active Grant
First Claim
Patent Images

1. A microarray hybridization device which comprises:

  • a flat substrate having a surface to which a microarray of reactive moieties can be attached, liquid barrier means juxtaposed with said surface to create a chamber in which said microarray is located, and means closing said chamber so said device may be manipulated without loss of liquid target solution that fills said chamber except for a gaseous bubble included therein, said barrier means having inwardly facing surfaces which border said chamber, which surfaces are formed with a plurality of bubble-fracturing elements that extend laterally into said chamber so that, when said device is moved so that a liquid target solution in said chamber moves along said surface from one boundary of said chamber to another boundary, a bubble initially in said chamber is ruptured into a plurality of microbubbles that then assure very effective distribution of the liquid target solution in said chamber across the entire microarray, driven by movement of said microbubbles.

View all claims
  • 1 Assignment
Timeline View
Assignment View
    ×
    ×