Immunodiagnostic device having a desiccant incorporated therein
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Abstract
A device for assaying biological fluids for molecules contained therein comprising a container, material situated in the container for absorbing fluid and in communication with an antibody or antigen impregnated matrix, wherein the matrix is accessible to the exterior of the container through a funnel shaped aperture in the roof of the container. Further features include a chemical drying agent associated with the container for absorbing moisture, thereby preventing inactivation of the assay reagents, and a filter situated above the antibody or antigen impregnated matrix, and in communication with the matrix through the aperture in the roof of the container. The filter removes interfering substances present in the biological fluids, and provides protein blocking agents to the matrix material for decreasing the background of the assay.
69 Citations
45 Claims
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1-25. -25. (canceled)
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26. A device for performing diagnostic assays of biological fluids for molecules contained therein, the device comprising
a container comprising a top section and a bottom section; -
a means for absorbing biological fluid in communication with antibody or antigen impregnated matrix material, said impregnated matrix material being accessible to the exterior of said container through an aperture in the top section; and
a filter means in communication with said impregnated matrix material, said filter means comprising a reagent for removing interfering substances present in said biological fluids. - View Dependent Claims (27, 28, 29, 30, 31, 32, 33, 34)
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- 35. A method of impregnating immunochemicals onto matrix material useful in immunodiagnostic assays, the method comprising dissolving said immunochemicals in solution, forming a thin stream of said solution, fragmenting said thin stream into droplets, applying a charge to said droplets, passing said charged droplets through an electric field thereby deflexing said droplets in a predetermined pattern onto said matrix material.
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37. A device for performing diagnostic assays of biological fluids for molecules contained therein, the device comprising
a means for absorbing biological fluid in communication with matrix material impregnated with immunochemicals selected from the group comprising antibody or antigen, wherein said matrix is impregnated by dissolving said immunochemicals in solution, forming a thin stream of said solution, fragmenting said thin stream into droplets, applying a charge to said droplets, passing said charged droplets through an electric field thereby deflexing said droplets in a predetermined pattern onto said matrix material.
Specification