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Therapeutic device for the selective cytoreduction treatment of an obstruction in a natural lumen or passage of the human or animal body

  • US 20050113748A1
  • Filed: 12/22/2004
  • Published: 05/26/2005
  • Est. Priority Date: 07/13/1994
  • Status: Active Grant
First Claim
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1. A therapeutic device intended for substantially fully intracorporeal insertion for treatment of an obstruction in the prostatic portion of a male urethra, comprising:

  • a non-biodegradable element that is designed to be placed and retained in a prostatic portion of the male urethra to maintain a channel, said element being sufficiently flexible to conform to the urethra, but sufficiently rigid to maintain the channel for urine flow in the prostatic portion, the channel providing for passage of urine from upstream of the obstruction to downstream of the obstruction; and

    a cytoreductive agent that causes reduction of the obstruction, said cytoreductive agent being positioned along said element, so as to treat the obstruction of the prostatic portion of the male urethra when said element is retained in the prostatic portion of the male urethra, wherein the reductive effect is through direct contact of said element with cells of the obstruction and even without removing the device from the urethra, the reductive effect ceases when the direct contact ceases, and wherein said device further comprises a withdrawal thread and is non-traumatically removable from the male urethra by said withdrawal thread following treatment of the obstruction.

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