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Androgen pharmaceutical composition and method for treating depression

  • US 20050118242A1
  • Filed: 04/20/2004
  • Published: 06/02/2005
  • Est. Priority Date: 08/30/2000
  • Status: Abandoned Application
First Claim
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1. A method of treating, preventing or reducing the risk of developing a depressive disorder in a subject in need thereof, comprising:

  • administering a depressive-disorder-effective amount of a composition to an area of skin of the subject for delivery of a steroid in the testosterone synthetic pathway to blood serum of the subject, wherein the composition comprises;

    (a) about 0.01% to about 70% of the steroid in the testosterone synthetic pathway;

    (b) about 0.01% to about 50% penetration enhancing agent;

    (c) about 0.01% to about 50%. thickening agent; and

    (d) about 30% to about 98% lower alcohol;

    wherein.the composition is capable of releasing the steroid after applying the composition to the skin at a rate and duration that delivers at least about 10 μ

    g per day of the steroid to the blood serum of the subject; and

    the percentages are on a weight to weight basis of the composition.

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