Polymer arrays
First Claim
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1. A substrate with a surface comprising a plurality of polypeptides with different, known sequences bound to the surface in positionally defined locations, at a density exceeding 400 different polypeptides occupying a total area of less than 1 cm2 on said substrate, each of said polypeptides having a different polypeptide sequence.
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Abstract
The present invention provides methods and apparatus for sequencing, fingerprinting and mapping biological macromolecules, typically biological polymers. The methods make use of a plurality of sequence specific recognition reagents which can also be used for classification of biological samples, and to characterize their sources.
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1 Claim
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1. A substrate with a surface comprising a plurality of polypeptides with different, known sequences bound to the surface in positionally defined locations, at a density exceeding 400 different polypeptides occupying a total area of less than 1 cm2 on said substrate, each of said polypeptides having a different polypeptide sequence.
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