Insulinotropic hormone derivatives and uses thereof

• US 20050119178A1
• Filed: 06/21/2004
• Published: 06/02/2005
• Est. Priority Date: 05/05/1986
• Status: Active Grant

• Current Assignee: The General Hospital Corporation (Mass General Brigham, Inc.)
• Original Assignee: The General Hospital Corporation (Mass General Brigham, Inc.)
• Inventors: Habener, Joel F.
• Granted Patent: US 7,138,486 B2
• Time in Patent Office: Days
• US Class Current: 530/308
• CPC Class Codes: A61K 38/26 Glucagons
• CPC Class Codes: C07K 14/605 Glucagons

Abstract

Derivatives of glucagon-like peptide I (GLP-1) and especially GLP-1(7-36) have been found to have insulinotropic activity. The invention pertains to the use of GLP-1(7-36) for the treatment of type II diabetes mellitus.

Claims

1-30. -30. (canceled)

31. A composition comprising an acid addition salt of GLP-I(7-37).

32. A composition comprising a carboxylate salt of GLP-I(7-37).