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Generation of living tissue in vivo using a mold

  • US 20050123520A1
  • Filed: 05/04/2004
  • Published: 06/09/2005
  • Est. Priority Date: 05/05/2003
  • Status: Abandoned Application
First Claim
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1. A method of making a living tissue construct having a predetermined shape, the method comprising obtaining a negative mold having a defined shape;

  • suspending isolated tissue precursor cells in a hydrogel to form a liquid hydrogel-precursor cell composition;

    filling the liquid hydrogel-precursor cell composition into the mold;

    implanting the filled mold into a living host for a time sufficient to enable the tissue precursor cells to form tissue;

    removing the mold from the living host; and

    removing the living tissue construct from the mold.

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