Apparatus and methods for treating stroke and controlling cerebral flow characteristics

• US 20050124973A1
• Filed: 01/20/2005
• Published: 06/09/2005
• Est. Priority Date: 08/22/2001
• Status: Abandoned Application

• Current Assignee: W. L. Gore & Associates (W.L. Gore & Associates)
• Original Assignee: W. L. Gore & Associates (W.L. Gore & Associates)
• Inventors: Dorros, Gerald, Hogendijk, Michael, Parodi, Juan Carlos, Schonholz, Claudio Javier
• Application Number:
  US11/039,607
• Publication Number:
  US 20050124973A1
• Time in Patent Office: Days
• US Class Current: 604/509
• CPC Class Codes: A61B 17/12022 Occluding by internal devices, e.g. balloons or releasable wires plugging an opening in the wall of an organ A61B17/0057; occluders for the cervical canal A61F6/146; vas deferens occluders A61F6/20
• CPC Class Codes: A61B 17/12109 in a blood vessel
• CPC Class Codes: A61B 17/12136 Balloons
• CPC Class Codes: A61B 17/22 Implements for squeezing-off ulcers or the like on the inside of inner organs of the body; Implements for scraping-out cavities of body organs, e.g. bones; Calculus removers; Calculus smashing apparatus; Apparatus for removing obstructions in blood vessels, not otherwise provided for dilators A61M29/00
• CPC Class Codes: A61B 17/22031 Gripping instruments, e.g. forceps, for removing or smashing calculi A61B17/221 takes precedence
• CPC Class Codes: A61B 17/221 Gripping devices in the form of loops or baskets for gripping calculi or similar types of obstructions surgical snare instruments A61B17/32056
• CPC Class Codes: A61B 17/3207 Atherectomy devices working by cutting or abrading; Similar devices specially adapted for non-vascular obstructions A61B17/32037 takes precedence; endoscopic cutting instruments A61B17/320016
• CPC Class Codes: A61B 2017/22034 for gripping the obstruction or the tissue part from inside
• CPC Class Codes: A61B 2017/3435 using everted sleeves
• CPC Class Codes: A61M 2025/09008 having a balloon
• CPC Class Codes: A61M 2025/09083 having a coil around a core
• CPC Class Codes: A61M 2025/09166 having radio-opaque features
• CPC Class Codes: A61M 2025/1052 for temporarily occluding a vessel for isolating a sector
• CPC Class Codes: A61M 25/1002 characterised by balloon shape A61M25/1006, A61M25/1009 take precedence

Abstract

Apparatus and methods for treatment of stroke are provided. In a preferred embodiment, the present invention disposes at least one catheter having a distal occlusive member in either the common carotid artery (CCA) or both the vertebral artery (VA) and the CCA on the hemisphere of the cerebral occlusion. Blood flow in the opposing carotid and/or vertebral arteries may be inhibited. Retrograde or antegrade flow may be provided through either catheter independently to effectively control cerebral flow characteristics. Under such controlled flow conditions, a thrombectomy device may be used to treat the occlusion, and any emboli generated are directed into the catheter(s).

Claims

1-25. -25. (canceled)

26. Apparatus suitable for manipulating cerebral blood flow characteristics, the apparatus comprising:

a catheter configured for introduction into a first blood vessel, having proximal and distal ends, a lumen extending therebetween, and an occlusive element affixed to the distal end, the occlusive element having an opening that communicates with the lumen, the occlusive element having a contracted position suitable for transluminal insertion and an expanded position wherein the occlusive element occludes antegrade flow in a vessel; and

at least one flow control device adapted for introduction into a second blood vessel, having proximal and distal ends and a flow control element disposed at the distal end;

wherein when the occlusive element and flow control device are deployed in the first and second blood vessels, they control perfusion in a third blood vessel distal to the first and second blood vessels.

27. The apparatus of claim 26, further comprising a thrombectomy wire configured to be advanced into the third blood vessel.

28. The apparatus of claim 26, wherein the occlusive element comprises an inflatable balloon.

29. The apparatus of claim 28, wherein the inflatable balloon forms a tapered entrance to the lumen when the inflatable balloon is inflated.

30. The apparatus of claim 26, wherein the flow control element is an inflatable balloon.

31. The apparatus of claim 26, wherein the third blood vessel is an MCA.

32. The apparatus of claim 27, wherein the third blood vessel is an MCA.