Hemofiltration system and method based on monitored patient parameters, supervisory control of hemofiltration, and adaptive control of pumps for hemofiltration
First Claim
1. A hemofiltration system for fluid removal from the blood of a patient, comprising:
- a pump capable of pumping a liquid selected from the group consisting of infusate, drained fluid, and blood in the hemofiltration system;
a sensor for measuring the flow rate of fluid in the medical system generated by at least one pump, the flow rate sensor providing flow rate data signals correlated to the fluid flow rate;
a supervisory controller operably connectable to the at least one pump and operably connected to the flow rate sensor; and
at least one monitor for measuring at least one predetermined patient parameter;
said least one patient parameter monitor providing patient parameter data signals correlated to said at least one patient parameter, wherein the controller is operably connected to said at least one monitor, the controller receiving the flow rate data signals and the patient parameter data signals and analyzing the flow rate data signals and the patient parameter data signals utilizing fuzzy logic having at least one predetermined supervisory rule, and then providing an output signal for the at least one pump to adjust, as necessary on a periodic ongoing basis, the flow rate of liquid generated by the at least one pump for regulating fluid removal from the patient'"'"'s blood.
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Abstract
A multipurpose hemofiltration system and method are disclosed for the removal of fluid and/or soluble waste from the blood of a patient. The system continuously monitors the flow rates of drained fluid, blood, and infusate. When necessary, the pumping rates of the infusate, drained fluid and blood are adjusted to remove a preselected amount of fluid from the blood in a preselected time period. A supervisory controller can monitor patient parameters, such as heart rate and blood pressure, and adjust the pumping rates accordingly. The supervisory controller uses fuzzy logic to make expert decisions, based upon a set of supervisory rules, to control each pumping rate to achieve a desired flow rate and to respond to fault conditions. An adaptive controller corrects temporal variations in the flow rate based upon an adaptive law and a control law.
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Citations
6 Claims
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1. A hemofiltration system for fluid removal from the blood of a patient, comprising:
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a pump capable of pumping a liquid selected from the group consisting of infusate, drained fluid, and blood in the hemofiltration system;
a sensor for measuring the flow rate of fluid in the medical system generated by at least one pump, the flow rate sensor providing flow rate data signals correlated to the fluid flow rate;
a supervisory controller operably connectable to the at least one pump and operably connected to the flow rate sensor; and
at least one monitor for measuring at least one predetermined patient parameter;
said least one patient parameter monitor providing patient parameter data signals correlated to said at least one patient parameter,wherein the controller is operably connected to said at least one monitor, the controller receiving the flow rate data signals and the patient parameter data signals and analyzing the flow rate data signals and the patient parameter data signals utilizing fuzzy logic having at least one predetermined supervisory rule, and then providing an output signal for the at least one pump to adjust, as necessary on a periodic ongoing basis, the flow rate of liquid generated by the at least one pump for regulating fluid removal from the patient'"'"'s blood. - View Dependent Claims (2)
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3. A hemofiltration system for fluid removal from the blood of a patient, comprising:
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a pump capable of pumping a liquid selected from the group consisting of infusate, drained fluid, and blood in the hemofiltration system;
a flow rate sensor for measuring the flow rate of the liquid generated by the at least one pump, the flow rate sensor providing flow rate data signals correlated to the liquid flow rate; and
an adaptive controller operably connectable to the at least one pump and operably connected to the flow rate sensor, the controller receiving the flow rate data signals and generating an output signal for adjusting the pumping rate of the liquid generated by the at least one pump, the controller providing the output signal for the at least one pump on a periodic ongoing basis, the controller using an adaptive law to generate a set of controller parameters for correcting time-dependent deviations of the flow rate from a predetermined flow rate, and using a control law to generate the output signal from the set of controller parameters for adjusting the pumping rate of the liquid generated by the at least one pump to achieve the predetermined flow rate for regulating fluid removal from the patient'"'"'s blood. - View Dependent Claims (4)
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5. A method of controlling a pump in a hemofiltration system, comprising:
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measuring the flow rate of a liquid selected from the group consisting of infusate, drained fluid, and blood generated by the pump to obtain flow rate data signals correlated to the fluid flow rate;
measuring at least one patient parameter to obtain patient parameter data signals correlated to said at least one patient parameter;
analyzing the flow rate data signals and the patient parameter data signals utilizing fuzzy logic having at least one predetermined supervisory rule; and
providing an output signal to the pump to adjust, as necessary on a periodic ongoing basis, the flow rate of liquid generated by the pump for regulating fluid removal from the patient'"'"'s blood.
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6. A method of controlling a pump in an ultrafiltration system, comprising:
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measuring a flow rate of a liquid selected from the group consisting of infusate, drained fluid, and blood in the hemofiltration system generated by the pump to obtain flow rate data signals correlated to the liquid flow rate;
generating a set of controller parameters from the flow rate signals for correcting time-dependent deviations of the flow rate from the predetermined flow rate;
generating an output signal using a control law from the set of controller parameters, the output signal capable of adjusting the pumping rate of liquid generated by the pump to achieve a predetermined flow rate; and
providing the output signal to the pump on a periodic ongoing basis to correct the deviations of the flow rate from the predetermined flow for regulating fluid removal from the patient'"'"'s blood.
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Specification