System and method for acquiring breathing pattern signals from intracardiac electrograms and its use for heart failure therapy decision making and disease monitoring

• US 20050137487A1
• Filed: 12/19/2003
• Published: 06/23/2005
• Est. Priority Date: 12/19/2003
• Status: Active Grant

• Current Assignee: Cardiac Pacemakers Incorporated (Boston Scientific Corporation)
• Original Assignee: Cardiac Pacemakers Incorporated (Boston Scientific Corporation)
• Inventors: Zhu, Qingsheng, Spinelli, Julio, Hatlestad, John, Kenknight, Ken
• Granted Patent: US 7,184,817 B2
• Time in Patent Office: Days
• US Class Current: 600/513
• CPC Class Codes: A61B 5/0031 Implanted circuitry
• CPC Class Codes: A61B 5/0816 Measuring devices for examining respiratory frequency measuring frequency of electric signals G01R23/00
• CPC Class Codes: A61B 5/352 Detecting R peaks, e.g. for synchronising diagnostic apparatus; Estimating R-R interval

Abstract

An ICD processing system for acquiring breathing pattern signals from intracardiac electrograms obtained from implantable cardiac devices. The system may include both an implantable ICD device and an external processing system. Both the ICD module and the external processing system processing data to generate a representation for the respiration rate for a patient using intracardiac electrogram data obtained by the ICD device. The ICD module and the external processing module communicate with each other to pass collected patient data from the ICD module to the external processing system. The ICD module and the external processing module process the electrogram data to obtain an processed data representation of the respiration data which is used to estimate the respiration rate.

Claims

1. A system providing acquiring breathing pattern signals from intracardiac electrograms obtained from implantable cardiac devices, the system comprising:

a cardiac data sample input module for receiving intracardiac electrograms data;

a cardiac data over-sampling and filtering module for generating a uniform data rate respiration data signal data from the received intracardiac electrogram data;

a cardiac data resampling module for generating respiration signal data from the uniform data rate respiration data signal data;

wherein the respiration signal data represents a signal corresponding to the respiration for a patient.

2. The system according to claim 1, wherein the intracardiac electrograms data corresponds to a non-uniform sampled signal.

3. The system according to claim 2, wherein the cardiac data over-sampling and filtering module interpolates the received intracardiac electrograms data to generate a uniform rate data signal.

4. The system according to claim 3, wherein the cardiac data over-sampling and filtering module further low-pass filters the uniform rate data signal to generate the uniform data rate respiration data signal.

5. The system according to claim 2, wherein the cardiac data resampling module resamples the uniform data rate respiration data signal at a desired data rate.

6. The system according to claim 2, wherein the respiration signal data is used to provide an estimate for the respiration rate of a patient.

7. The system according to claim 6, wherein the respiration signal data is used to provide an estimate for the respiration tidal volume of a patient.

8. The system according to claim 1, wherein the cardiac data over-sampling and filtering module and the cardiac data resampling module are located within an ICD device.

9. The system according to claim 2, wherein the cardiac data over-sampling and filtering module and the cardiac data resampling module are located within a cardiac analysis processing system.

10. The system according to claim 2, wherein the respiration signal data is stored within a data storage module for subsequent use.

11. A method for acquiring breathing pattern signals from intracardiac electrograms obtained from implantable cardiac devices, the method comprising:

obtaining peak-to-peak intracardiac electrograms signal data;

generating respiration sample data from the peak-to-peak intracardiac electrograms signal data;

interpolating the respiration sample data to create a processed respiration signal data having an over-sampled uniform sample rate;

low-pass filtering the processed respiration signal data to generate a filtered respiration data signal; and

sub-sampling the filtered respiration data signal at a desired rate to generate an estimated respiration data signal.

12. The method according to claim 11, wherein the method further comprises:

generating a estimated respiration rate and estimated respiration tidal volume from the estimated respiration signal.

13. The method according to claim 12, wherein the method further comprises:

generating a estimated heart rate and an estimated heart rate/respiration rate ratio; and

using the estimated respiration signal when the estimated heart rate/respiration rate ratio is greater than 2.

14. A computer data product containing computer readable data encoding instructions for implementing a computer implemented method for acquiring breathing pattern signals from intracardiac electrograms obtained from implantable cardiac devices, the method comprising:

obtaining peak-to-peak intracardiac electrograms signal data;

generating respiration sample data from the peak-to-peak intracardiac electrograms signal data;

interpolating the respiration sample data to create a processed respiration signal data having an over-sampled uniform sample rate;

low-pass filtering the processed respiration signal data to generate a filtered respiration data signal; and

sub-sampling the filtered respiration data signal at a desired rate to generate an estimated respiration data signal.

15. The computer data product according to claim 15, wherein the method further comprises:

generating a estimated respiration rate and estimated respiration tidal volume from the estimated respiration signal.

16. The computer data product according to claim 15, wherein the method further comprises:

generating a estimated heart rate and an estimated heart rate/respiration rate ratio; and

using the estimated respiration signal when the estimated heart rate/respiration rate ratio is greater than 2.