System and method for delivering a substance to a body cavity

• US 20050137529A1
• Filed: 10/07/2004
• Published: 06/23/2005
• Est. Priority Date: 10/07/2003
• Status: Active Grant

• Current Assignee: Northgate Technologies Incorporated
• Original Assignee: Northgate Technologies Incorporated
• Inventors: Mantell, Robert R.
• Granted Patent: US 7,704,223 B2
• Time in Patent Office: Days
• US Class Current: 604/129
• CPC Class Codes: A61B 17/3474 Insufflating needles, e.g. Veress needles
• CPC Class Codes: A61M 13/003 Blowing gases other than for carrying powders, e.g. for inflating, dilating or rinsing
• CPC Class Codes: A61M 2202/0241 Anaesthetics; Analgesics
• CPC Class Codes: A61M 2202/0468 non-physiological
• CPC Class Codes: A61M 2210/1017 Peritoneal cavity

Abstract

A system and method for creating a medicated atmosphere in an organ, or body cavity is disclosed. The system includes a flexible aerosolization catheter that can be manipulated during use, a device for the introduction of the aerosolization catheter, a medication delivery apparatus configured to control delivery of a medication to the catheter, a gas delivery apparatus in communication with the catheter, a gas pressure relief apparatus configured to relieve pressure in the organ or body cavity, and a central controller in communication with the medication delivery apparatus, gas delivery apparatus, and gas pressure relief apparatus control of the various means. The method includes providing insufflation gas and an aerosol of medication to an organ or body cavity while controlling overall pressure in the organ or cavity. The method may also include re-entering a patient through at least one port to apply gas and an aerosolized medicament, in either a post-operative procedure or in a chemotherapy context.

Claims

1. A system for delivering a substance to a body cavity of a patient, the system comprising:

a gas delivery channel configured for delivery of a gas to the body cavity of the patient;

a substance delivery channel configured for delivery of the substance to the body cavity of the patient; and

at least one pressure relief valve in communication with one of the gas and substance delivery channels for maintaining a pressure in the body cavity.

2. The system of claim 1, wherein the substance delivery channel comprises a nebulizing catheter adapted to aerosolize the substance in the body cavity.

3. The system of claim 2, wherein the body cavity comprises a peritoneum.

4. The system of claim 2, wherein the substance comprises an anti-adhesive.

5. The system of claim 2, wherein the substance comprises an analgesic.

6. The system of claim 2, wherein the substance comprises an antibiotic.

7. A system for providing a controlled environment in a body cavity of a patient, the system comprising:

an insufflator adapted to provide a supply of gas to the body cavity via a gas line;

a nebulizing catheter in communication with a source of nebulizing gas and a source of fluid for nebulizing;

at least one pressure relief valve in communication one of the gas line and the source of nebulizing gas, the at least one pressure relief valve for maintaining a pressure in the body cavity; and

a central controller in communication with the insufflator, the source of nebulizing gas, the source of fluid and the pressure relief valve to coordinate delivery of fluid and gas, while maintaining a desired pressure in the body cavity.

8. The system of claim 7, wherein the at least one pressure relief valve comprises one of an electrically and pneumatically controllable valve.

9. The system of claim 7, wherein the at least one pressure relief valve comprises a passive mechanical valve.

10. A method for providing a controlled laparoscopic environment in a body cavity of a patient, the method comprising:

providing a gas to the body cavity;

providing a substance to the body cavity;

distributing the substance within the body cavity; and

monitoring a pressure applied to the patient peritoneum and adjusting the pressure to a desired pressure.

11. A method of providing repeated application of a substance to a body cavity of a patient, the method comprising:

implanting a port in an abdominal wall of the patient;

connecting a source of insufflation gas with the port and injecting insufflation gas;

connecting a substance delivery mechanism to the port;

injecting a substance into the body cavity;

removing the source of insufflation gas and the substance delivery mechanism.

12. The method of claim 11, wherein the substance is a chemotherapy drug.

13. A system for use in a minimally invasive procedure to deliver a substance to a body cavity of a patient, the system comprising:

a fluid dispensing controller in communication with a gas supply and the substance;

a catheter configured for insertion into the body cavity, the catheter comprising;

a gas delivery channel configured for delivery of gas from the gas supply to the body cavity of the patient, wherein the gas delivery channel comprises an only source of gas provided to the body cavity; and

a substance delivery channel configured for delivery of the substance to the body cavity of the patient;

at least one pressure relief valve in communication with one of the gas and substance delivery channels for maintaining a pressure in the body cavity; and

wherein gas delivered to the body cavity via the gas delivery channel both distends the body cavity and nebulizes the substance.

14. The system of claim 13, wherein the pressure relief valve comprises a passive pressure relief valve configured for positioning adjacent the body cavity.

15. The system of claim 13, wherein the pressure relief valve comprises an active pressure relief valve positioned adjacent the gas supply and in communication with the body cavity via an external pressure sense line.

16. The system of claim 13, wherein the fluid dispensing controller comprises a housing sized to removably receive a disposable syringe.

17. The system of claim 16, further comprising a disposable catheter defining at least a portion of the gas delivery channel, the disposable catheter operatively connected with the disposable syringe via one of a direct connection or a disposable tube.

18. The system of claim 13, further comprising a plurality of syringes in communication with the substance delivery channel and independently controllable by the fluid dispensing controller to provide a plurality of fluids to the substance delivery channel.

19. The system of claim 18, wherein the plurality of syringes are in communication with the substance delivery channel via a mixing chamber.

20. The system of claim 19, wherein the mixing chamber is connected to a pressurized gas supply.