Variable density braid stent

• US 20050137680A1
• Filed: 12/22/2003
• Published: 06/23/2005
• Est. Priority Date: 12/22/2003
• Status: Active Grant

• Current Assignee: Stryker European Operations Holdings, LLC (Stryker Corporation)
• Original Assignee: Stryker Corporation, Stryker Nv Operations Limited (Stryker Corporation)
• Inventors: Molaei, Masoud, Gerberding, Brent C., Ortiz, John, Musbach, Frank
• Granted Patent: US 7,763,011 B2
• Time in Patent Office: Days
• US Class Current: 623/1.160
• CPC Class Codes: A61F 2/90 characterised by a net-like or mesh-like structure
• CPC Class Codes: A61F 2002/823 Stents, different from stent-grafts, adapted to cover an aneurysm
• CPC Class Codes: A61F 2250/0015 differing in density or specific weight
• CPC Class Codes: A61F 2250/0023 differing in porosity
• CPC Class Codes: A61F 2250/0048 differing in mechanical expandability, e.g. in mechanical, self- or balloon expandability
• CPC Class Codes: D04C 1/06 Braid or lace serving particular purposes

Abstract

A stent comprises at least one stent member woven to form a substantially tubular body that defines a flow path. The tubular body comprises a first region and a second region. In the first region the at least one stent member defines a plurality of first region openings and in the second region at least one first portion of the at least one member and at least one second portion of the at least one member are engaged together to form at least one primary strand. The at least one primary strand defines a plurality of second region openings. The at least one of the plurality of second region openings is in fluid communication with the flow path. The plurality of second region openings provide the second region with a greater porosity than the first region.

Claims

1. A stent comprising:

at least one stent member, the at least one stent member interwoven to form a substantially tubular body, the substantially tubular body defining a flow path therethrough, the substantially tubular body comprising a first region and a second region, the second region being immediately adjacent to the first region,

in the first region the at lease one stent member defining a plurality of first region openings,

in the second region at least one first portion of the at least one member and at least one second portion of the at least one member being engaged together to form at least one primary braid, the at least one primary braid defining a plurality of second region openings, at least one of the plurality of second region openings being in bodily fluid communication with the flow path, the plurality of second region openings providing the second region with a greater porosity than the first region.

2. The stent of claim 1 wherein the substantially tubular body further comprises a third region, the third region being immediately adjacent to the second region, in the third region at least one first portion of the at least one primary braid and at least one second portion of the primary braid being engaged together to form at least one secondary braid, the at least one secondary braid defining a plurality of third region openings, at least one of the plurality of third region openings being in bodily fluid communication with the flow path, the plurality of third region openings providing the third region with a greater porosity than the first region.

3. The stent of claim 1 wherein the at least one of the plurality of second region openings has a greater area than any one of the plurality of first region openings.

4. The stent of claim 1 wherein each of the plurality of first region openings has an area of about 0.005 mm² to about 0.15 mm².

5. The stent of claim 1 wherein the at least one of the plurality of second region openings has an area of about 0.05 mm² to about 0.3 mm².

6. The stent of claim 1 wherein the at least one member has a diameter of about 0.001 inch to about 0.00125 inch.

7. The stent of claim 1 wherein the at least one first portion of the at least one member and the at least one second portion of the at least one member are braided together to form the at least one primary braid.

8. The stent of claim 2 wherein the at least one of the plurality of third region openings has a greater area than any one of the plurality of first region openings.

9. The stent of claim 2 wherein the at least one of the plurality of third region openings has a greater area than any one of the second region openings.

10. The stent of claim 2 wherein the at least one of the plurality of third region openings has an area of about 0.05 mm² to about 0.3 mm².

11. The stent of claim 2 wherein the at least one first portion of the at least one primary braid and the at least one second portion of the at least one primary braid are braided together to form the at least one secondary braid.

13. The stent of claim 1 wherein at least a portion of the tubular body is self-expandable, balloon expandable and/or hybrid expandable.

14. The stent of claim 1 wherein at least a portion of one of the first region and the second region is balloon expandable and at least different portion of one of the first region and the second region is self-expandable.

15. The stent of claim 1 wherein the at least one stent member is at least partially constructed from a shape memory material.

16. The stent of claim 1 wherein the at least one stent member is at least partially cons ted from nitinol.

17. The stent of claim 1 wherein at least a portion of the stent is coated with at least one therapeutic agent.

18. (canceled)

19. (canceled)

20. (canceled)

21. (canceled)

22. A stent for insertion into a body lumen having at least one aneurysm therein, the stent comprising:

at least one stent member, the at least one stent member forming a substantially tubular body, the substantially tubular body defining a flow path therethrough, the substantially tubular body comprising a first region and a second region longitudinally and immediately adjacent thereto,

in the first region the at least one stent member defining a plurality of first region openings, in the second region the at least one stent member defining a plurality of second region openings,

each of the plurality of first region openings being smaller in area than each of the plurality of second region openings, the area of each first region opening being sized to restrict passage of blood from the flow path through the first region openings to cause stagnation of the at least one aneurysm adjacent to the first region, the area of each second region opening being sized to allow free flow of blood through the second region openings to at least one perforator vessel adjacent to the second region.

23. The stent of claim 22 wherein the at least one stent member is interwoven to form the substantially tubular stent body.

24. The stent of claim 22 comprising a plurality of interconnected stent members which form the substantially tubular body.

25. The stent of claim 24 wherein at least one of the plurality of interconnected stent members are interwoven.

26. The stent of claim 23 further comprising a third region, wherein the third region is longitudinally and immediately adjacent the second region, in the third region the at least one stent member defines a plurality of third region openings, each of the plurality of third region openings being larger in area than each of the second region openings.

27. The stent of claim 26 wherein the first region has a proximal end and a distal end, the second region extending from at least one of the distal end and the proximal end of the first region.

28. The stent of claim 26 wherein a proximal portion of the second region extends from the proximal end of the first region and a distal portion of the second region extends from the distal end of the first region.

29. The stent of claim 26 wherein the first region has a proximal end and a distal end, a proximal portion of the second region extends from the proximal end of the first region and a distal portion of the second region extends from the distal end of the first region, a proximal portion of the third region extends from the proximal portion of the second region, a distal portion of the third region extends from the distal portion of the second region.

30. A stent for insertion into a body lumen having at least one aneurysm therein, the stent comprising:

at least one stent member, the at least one stent member forming a substantially tubular body, the substantially tubular body defining a flow path therethrough, the substantially tubular body comprising a plurality of regions which are longitudinally adjacent one another,

in each of the regions the at least one stent member defining a plurality of openings, wherein when the stent is inserted into a body lumen at least one of the regions is positioned immediately adjacent to at least one aneurysm, each of the plurality of openings in the at least one region are sized such that blood flow to the at least one aneurysm will stagnate but will be able to flow through the openings to at least one perforator vessel in fluid communication with the body lumen and flow path.

31. The stent of claim 30 wherein the at least one stent member comprises a plurality of stent members.

32. The stent of claim 31 wherein the plurality of stent members are interwoven.

33. The stent of claim 32 wherein the substantially tubular body comprises a first region and a second region, the second region being immediately and longitudinally adjacent to at least one end of the first region.

34. The stent of claim 33 wherein the first region the plurality of stent members define a plurality of first region openings and in the second region die plurality of stent members define a plurality of second region openings, each of the plurality of first region openings being smaller in area than each of the plurality of second region openings, the area of each first region opening being sized to restrict passage of blood from the flow path through the first region openings to cause stagnation of at least one aneurysm adjacent to the first region, the area of each second region opening being sized to allow free flow of blood through the second region openings.

35. A method for treating at least one aneurysm within a body lumen comprising the steps of:

providing a stent having at least one stent member, the at least one stent member forming a substantially tubular body, the substantially tubular body defining a flow path theretbrough, the substantially tubular body comprising a plurality of regions which are longitudinally adjacent one another, in each of the regions the at least one stent member defining a plurality of openings;

positioning the stent with in the body lumen such that at least one of the regions underlies the at least one an aneurysm, blood within the body lumen flowing through the flow path, each of the plurality of openings in the at least one region are sized such that blood flow to the at least one aneurysm will stagnate but will be able to flow through the openings to at least one perforator in fluid communication with the body lumen and flow path;

providing a flow of blood through the openings of the at least one region which is sufficiently restricted to result in stagnation of the at least one aneurysm as a result of the size of the area of the at least one region, the size of the area of the openings of the at least one region being sufficient to provide a desired flow of blood to at least one perforator vessel adjacent to the at least one region and in fluid communication with the body lumen.