Method of reducing the effect of direct and mediated interference current in an electrochemical test strip

• US 20050139489A1
• Filed: 10/29/2004
• Published: 06/30/2005
• Est. Priority Date: 10/31/2003
• Status: Abandoned Application

• Current Assignee: LifeScan Scotland Limited (Johnson & Johnson)
• Original Assignee: LifeScan Scotland Limited (Johnson & Johnson)
• Inventors: Marshall, Robert, Whyte, Lynsey, Baskeyfield, Damian Edward Haydon, Leiper, Elaine, Davies, Oliver William Hardwicke
• Application Number:
  US10/977,086
• Publication Number:
  US 20050139489A1
• Time in Patent Office: Days
• US Class Current: 205/775
• CPC Class Codes: A61B 5/14532 for measuring glucose, e.g. by tissue impedance measurement
• CPC Class Codes: A61B 5/1486 using enzyme electrodes, e.g. with immobilised oxidase
• CPC Class Codes: A61B 5/150022 for capillary blood or interstitial fluid
• CPC Class Codes: A61B 5/150282 for piercing elements, e.g. blade, lancet, canula, needle
• CPC Class Codes: A61B 5/150358 Strips for collecting blood, e.g. absorbent optical reagent test strips G01N21/8483; chemical reagent test strips G01N33/4875, G01N33/52
• CPC Class Codes: A61B 5/150435 Specific design of proximal end
• CPC Class Codes: A61B 5/150503 Single-ended needles hollow piercing element tip design A61B5/150396, needle sets for catheters A61M25/06, needles for bringing media into the body A61M5/32
• CPC Class Codes: C12Q 1/001 Enzyme electrodes
• CPC Class Codes: C12Q 1/006 for glucose
• CPC Class Codes: G01N 27/3274 Corrective measures, e.g. error detection, compensation for temperature or hematocrit, calibration coding of calibration information G01N33/48771
• CPC Class Codes: Y02A 90/10 Information and communication technologies [ICT] supporting adaptation to climate change, e.g. for weather forecasting or climate simulation

Abstract

The present invention is directed to a method of reducing interferences in an electrochemical sensor wherein the method includes the step of measuring a first current at a first working electrode, the first working electrode being covered by an active reagent layer, the step of measuring a second current at a second working electrode, the second working electrode being covered by an inactive reagent layer and the step of calculating a corrected current value representative of a glucose concentration using a ratio of an active area of the first working electrode to an inactive area of the second working electrode. The present invention is further directed to a method of reducing interferences in an electrochemical sensor wherein the method includes the step of measuring a first current at a first working electrode, the first working electrode being covered by an active reagent layer, the step of measuring a second current at a second working electrode, wherein the active reagent layer is disposed on an active region of the second working electrode and an inactive region of the second working electrode is covered by an inactive reagent layer and the step of calculating a corrected current value representative of a glucose concentration using a ratio of an active region on the first and second working electrodes and an inactive region on the second working electrode.

Claims

1. A method of reducing interferences in an electrochemical sensor comprising:

measuring a first current at a first working electrode, said first working electrode being covered by an active reagent layer;

measuring a second current at a second working electrode, said second working electrode being covered by an inactive reagent layer; and

calculating a corrected current value representative of a glucose concentration which subtracts said second current from said first current.

2. A method of reducing interferences in an electrochemical sensor comprising:

measuring a first current at a first working electrode, said first working electrode being covered by an active reagent layer;

measuring a second current at a second working electrode, wherein said active reagent layer is disposed on an active region of said second working electrode and an inactive region of said second working electrode is covered by an inactive reagent layer; and

calculating a corrected current value representative of a glucose concentration using a ratio of an active region on said first and second working electrodes and an inactive region on said second working electrode.