Cardiovascular implant, method and device for its production, and its provision for surgery
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Accused Products
Abstract
A cardiovascular implant for use in surgery, in particular a heart valve with flaps, made substantially of biocompatible synthetic polymer material in the form of a three-dimensional structure, wherein the polymer material is substantially nonabsorbable under physiological conditions, and the implant, at least on part of its surface, is formed as a microporous nonwoven from microfibers of the polymer material, which permit colonization with cells.
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Citations
63 Claims
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1-26. -26. (canceled)
- 27. A cardiovascular implant for use in surgery made substantially of biocompatible synthetic polymer material in the form of a three-dimensional structure, wherein the polymer material is substantially nonabsorbable under physiological conditions, and the implant, at least on part of its surface, is formed as a microporous nonwoven from microfibers of the polymer material, which permit colonization with cells.
- 57. A method for producing a biohybrid implant made substantially of biocompatible synthetic polymer material in the form of a three-dimensional structure with a nonwoven-type surface, wherein a preform of the implant made of synthetic polymer material is colonized with human cells, initially with one or more of fibroblasts and smooth muscle cells, then colonized with endothelial cells in a surface cell layer.
Specification