White silver-containing wound care device

• US 20050147657A1
• Filed: 02/28/2005
• Published: 07/07/2005
• Est. Priority Date: 08/14/2003
• Status: Abandoned Application

• Current Assignee: Milliken & Company
• Original Assignee: Milliken & Company
• Inventors: Canada, T. Andrew, Kreider, Jason L., Sturm, Raymond C., Schuette, Robert L., Wiencek, K. Mark
• Application Number:
  US11/068,639
• Publication Number:
  US 20050147657A1
• Time in Patent Office: Days
• US Class Current: 424/445
• CPC Class Codes: A61K 2300/00 Mixtures or combinations of active ingredients, wherein at least one active ingredient is fully defined in groups A61K31/00 - A61K41/00
• CPC Class Codes: A61K 31/4172 Imidazole-alkanecarboxylic acids, e.g. histidine
• CPC Class Codes: A61K 33/38 Silver; Compounds thereof
• CPC Class Codes: A61K 33/42 Phosphorus; Compounds thereof
• CPC Class Codes: A61L 15/18 containing inorganic materials
• CPC Class Codes: A61L 15/44 Medicaments
• CPC Class Codes: A61L 15/46 Deodorants or malodour counteractants, e.g. to inhibit the formation of ammonia or bacteria
• CPC Class Codes: Y10T 442/2525 Coating or impregnation functions biologically [e.g., insect repellent, antiseptic, insecticide, bactericide, etc.]

Abstract

White wound care devices having a topically applied silver-based antimicrobial finish are provided. The finish consists essentially of at least one silver ion releasing compound and at least one binder compound. The finish may be applied to a target substrate, such as a fiber, fabric, or alginate to provide a single layer antimicrobial wound care device, in which the color of the original substrate is substantially maintained after application of the antimicrobial finish. Alternatively, the silver-containing substrate may be combined with one or more additional layers to provide a composite antimicrobial wound care device.

Claims

1. A wound care device having a substrate selected from the group consisting of fibers, fabrics, and alginates, at least a portion of said substrate being coated with a non-electrically conductive finish,

wherein said finish consists essentially of at least one binder material and at least one compound that releases silver ions,

wherein said coated wound care device exhibits an L* value, before use, of at least 74.0, when measured between wavelengths of 360 nm and 750 nm using a D65 light source and a 10°

observation angle.

2. The wound care device of claim 1, wherein said at least one silver ion-releasing compound is selected from the group consisting of silver ion exchange materials, silver particles, silver nanoparticles, silver salts, silver glass, and mixtures thereof.

3. The wound care device of claim 2, wherein said silver ion exchange material is selected from the group consisting of silver zirconium phosphate, silver calcium phosphate, silver zeolite, and mixtures thereof.

4. The wound care device of claim 3, wherein said silver ion exchange material is silver zirconium phosphate.

5. The wound care device of claim 1, wherein said wound care device exhibits an L* value of at least 80.0.

6. The wound care device of claim 5, wherein said wound care device exhibits an L* value of at least 90.0.

7. The wound care device of claim 1, wherein said substrate onto which said finish is applied includes additives selected from the group consisting of optical brighteners, dyes, opacifiers, and pigments.

8. The wound care device of claim 7, wherein said substrate comprises optical brighteners.

9. The wound care device of claim 1, wherein said substrate onto which said finish is applied is a fabric.

10. The wound care device of claim 9, wherein said substrate is a woven fabric.

11. The wound care device of claim 9, wherein said substrate is a nonwoven fabric.

12. The wound care device of claim 9, wherein said substrate is a knit fabric.

13. The wound care device of claim 12, wherein said knit fabric is a circular knit fabric comprised of polyester, nylon, and spandex, such that said knit fabric has a polyester side and a nylon side.

14. The wound care device of claim 1, wherein said device exhibits effective antimicrobial properties, as defined by a zone of inhibition against bacteria of at least 1 mm after two successive exposures.