Disposable reaction vessel with integrated optical elements
First Claim
1. A vessel for assaying liquids for analytes, comprising:
- a housing portion including at least one chamber for receiving a liquid therein; and
at least one optical element integrally formed with the housing portion for directing an incident light beam towards the at least one chamber and directing a light beam away from the at least one chamber after the light beam has interacted with analytes present in the liquid.
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0 Petitions
Accused Products
Abstract
The present invention provides disposable, semi-reusable, or single use reaction vessels with integrated optical elements for use with diffraction based assay systems. The vessel for assaying liquids for analytes includes a housing having at least one chamber or well for receiving a liquid therein and an optical element integrally formed with the housing for directing an incident light beam towards the well or chamber and directing a light beam away from the chamber after the light beam has interacted with analytes present in the liquid. The vessel may be test tube such as a blood collection tube, with or without, an optical element but having a pattern of analyte-specific receptors located on an inner surface of the tube wall so that when a liquid is introduced into the interior of the test tube analytes present in the liquid can bind with the pattern of analyte-specific receptors.
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Citations
33 Claims
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1. A vessel for assaying liquids for analytes, comprising:
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a housing portion including at least one chamber for receiving a liquid therein; and
at least one optical element integrally formed with the housing portion for directing an incident light beam towards the at least one chamber and directing a light beam away from the at least one chamber after the light beam has interacted with analytes present in the liquid. - View Dependent Claims (2, 3, 4, 5, 6, 7, 8, 9, 10, 11, 12, 13, 14, 15, 16, 17, 18, 19, 20, 21, 22)
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23. A vessel for assaying liquids for analytes using light diffraction, comprising:
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a housing portion including at least one chamber in a top surface thereof for receiving a liquid therein; and
a pre-selected pattern of analyte-specific receptors located on an inner surface of the at least one chamber so that when a liquid is introduced into the interior of the at least one chamber analytes present in the liquid can bind with the pattern of analyte-specific receptors, wherein when analytes bind with the pre-selected pattern of analyte-specific receptors a light beam incident on the pre-selected pattern of analyte-specific receptors is diffracted. - View Dependent Claims (24, 25, 26, 27, 28)
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29. A test tube, comprising;
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a cylindrical tube having a tube wall enclosing an interior and one closed end and one open end for receiving liquid into the interior of the cylindrical tube; and
a pre-selected pattern of analyte-specific receptors located on an inner surface of the tube wall so that when a liquid is introduced into the interior of the test tube analytes present in the liquid can bind with the pattern of analyte-specific receptors. - View Dependent Claims (30, 31)
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32. A test tube, comprising;
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a cylindrical tube having a tube wall enclosing an interior and one closed end and one open end for receiving liquid into the interior of the cylindrical tube;
a pre-selected pattern of analyte-specific receptors located on an inner surface of the tube wall so that when a liquid is introduced into the interior of the test tube analytes present in the liquid can bind with the pattern of analyte-specific receptors; and
at least one optical element integrally formed with the test tube wall for directing an incident light beam towards the at least one chamber and directing a light beam away from the at least one chamber after the light beam has interacted with analytes present in the liquid. - View Dependent Claims (33)
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Specification