Gastric stimulation responsive to sensing feedback

• US 20050149142A1
• Filed: 01/30/2004
• Published: 07/07/2005
• Est. Priority Date: 01/07/2004
• Status: Abandoned Application

• Current Assignee: Medtronic Incorporated (Medtronic Plc)
• Original Assignee: Medtronic Incorporated (Medtronic Plc)
• Inventors: Starkebaum, Warren L.
• Application Number:
  US10/768,995
• Publication Number:
  US 20050149142A1
• Time in Patent Office: Days
• US Class Current: 607/40
• CPC Class Codes: A61N 1/36007 of urogenital or gastrointestinal organs, e.g. for incontinence control

Abstract

In general, the invention is directed to methods and devices for monitoring one or more physiological parameters that reflect the activity of the stomach of a patient, and generating an electrical stimulation signal to induce symptoms of gastroparesis. The induced symptoms of gastroparesis may reduce a patients desire to consume large portions of food and thus provide an effective treatment for obesity.

Claims

1. A method for providing gastric stimulation responsive to sensed stomach activity of a patient, the method comprising:

sensing a physiological parameter of the patient that changes as a function of activity of a stomach of the patient; and

applying an electrical stimulation signal to the patient as a function of the sensed physiological parameter,

wherein the electrical stimulation signal induces symptoms of gastroparesis in the patient.

2. The method according to claim 1, wherein the physiological parameter includes at least one of a blood glucose concentration, an insulin concentration, a plasma ghrelin concentration, a body temperature, a distension of the stomach, a stomach acid concentration, a gastric electrical activity and a transabdominal impedance.

3. The method according to claim 1, further comprising:

measuring a characteristic of the physiological parameter; and

applying the electrical stimulation signal to the patient as a function of the measurement.

4. The method according to claim 3, wherein applying an electrical stimulation signal comprises applying the electrical stimulation signal for a period of time based on a level of a characteristic of the physiological parameter.

5. The method according to claim 4, further comprising applying the electrical stimulation signal for an increased period of time when the level exceeds a predetermined threshold.

6. The method according to claim 3, wherein the characteristic of the physiological parameter comprises at least one of a rate of change of the physiological parameter, an amplitude of the physiological parameter, a duration of the physiological parameter, an intensity of the physiological parameter and a concentration of the physiological parameter.

7. The method according to claim 3, wherein the characteristic of the physiological parameter is a first characteristic of a first physiological parameter, the method further comprising measuring a second characteristic of a second physiological parameter as a function of the first characteristic.

8. The method according to claim 1, wherein the method further comprises:

generating a communication to the patient in response to a characteristic of the sensed physiological parameter.

9. The method according to claim 8, wherein generating a communication comprises transmitting a wireless communication to an external module.

10. The method according to claim 8, wherein generating a communication comprises presenting notification of electrical stimulation to patient via external module.

11. The method of claim 1, wherein generating the communication comprises activating an implanted alert module.

12. The method according to claim 1, wherein the electrical stimulation signal is applied to the patient for a length of time as a function of the sensed physiological parameter.

13. The method according to claim 1, further comprising adjusting the electrical stimulation signal in response to feedback indicating gastric activity.

14. A system for providing gastric stimulation responsive to sensing feedback to induce symptoms in a patient comprising:

a sensor to sense a physiological parameter of a patient that changes as a function of activity of a stomach of the patient; and

a stimulator to generate an electrical stimulation signal to the patient as a function of the sensed physiological parameter.

15. The system according to claim 14, wherein the system further comprises a processor to analyze the physiological parameter over time for use in generating the electrical stimulation signal.

16. The system according to claim 14, further comprising a communication module to wirelessly transmit the communication to an external module.

17. The system according to claim 14, wherein the system further comprises an implanted alert module to notify the patient of the communication.

18. The system according to claim 14, wherein the sensor comprises a chemical sensor.

19. The system of claim 17, wherein the chemical sensor senses at least one of blood glucose concentration, insulin concentration and stomach acid concentration.

20. The system according to claim 14, wherein the sensor comprises a mechanical sensor.

21. The system of claim 20, wherein the mechanical sensor senses at least one of motion of the stomach and distension of the stomach.

22. The system according to claim 14, wherein the sensor comprises an electrical sensor.

23. The system of claim 22, wherein the electrical sensor senses at least one gastric electrical activity and transabdominal impedance.

24. The system according to claim 14, wherein the processor is implantable in the patient.

25. The system according to claim 14, wherein the processor is further configured to measure a characteristic of the physiological parameter and to compare the characteristic to a threshold.

26. The system according to claim 14, wherein the processor adjusts the electrical stimulation signal in response to feedback indicating gastric activity.

27. A system for providing gastric stimulation responsive to sensing feedback to induce symptoms in a patient comprising:

sensing means to sense a physiological parameter of a patient that changes as a function of activity of a stomach of the patient;

processing means to generate a communication to the patient as a function of the sensed physiological parameter; and

stimulating means to induce symptoms in the patient for treatment of obesity responsive to the processing means.

28. The system according to claim 27, wherein the processing means is further configured to measure a characteristic of the physiological parameter.

29. The system of claim 27, wherein the system further comprises a memory means to data associated with the sensed physiological parameter and the measured characteristic.

30. The system according to claim 27, wherein the system further comprises a communications means to notify the patient of a communications generated by the processing means as a function of the sensed physiological parameter.

31. The system according to claim 27, further comprising means for adjusting the electrical stimulation signal in response to feedback indicating gastric activity.

32. A computer-readable medium comprising instructions that cause a processor to provide gastric stimulation responsive to sensing feedback to induce symptoms in a patient, the instructions causing the processor to:

sense a physiological parameter of a patient that changes as a function of activity of a stomach of the patient; and

control application of an electrical stimulation signal transmitted to the patient for inducing gastroparesis symptoms as a function of the sensed physiological parameter.

33. The medium of claim 32, the instructions further causing the processor to:

measure a characteristic of the physiological parameter; and

control generation of an electrical stimulation signal transmitted to the patient for inducing gastroparesis symptoms as a function of the measurement.

34. The medium according to claim 33, the instructions further causing the processor to:

generate a communication to the patient in response to a characteristic of the sensed physiological parameter.

35. The medium according to claim 34, wherein the processor generates a communication by transmitting a wireless communication to an external module.

36. The medium according to claim 34, wherein the processor generates a communication by presenting notification of electrical stimulation to patient via external module.

37. The medium of claim 33, wherein the processor generates a communication by activating an implanted alert module.

38. The medium according to claim 33, wherein the electrical stimulation signal is applied to the patient for a length of time as a function of the sensed physiological parameter.

39. The medium according to claim 33, wherein the instructions cause the processor to adjust the electrical stimulation signal in response to feedback indicating gastric activity.