Pyrrolopyrimidine derivatives and analogs and their use in the treatment and prevention of diseases
First Claim
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1. A method for treating a disease comprising administering to a subject in need thereof an effective amount of an epidermal growth factor receptor modulating corresponding to Formula (I):
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Abstract
Described herein are compounds and compositions for modulating kinase activity, and methods for modulating kinase activity using the compounds and compositions. Also described herein are methods of using the compounds and/or compositions in the treatment and prevention of a variety of diseases and unwanted conditions in subjects.
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Citations
26 Claims
- 1. A method for treating a disease comprising administering to a subject in need thereof an effective amount of an epidermal growth factor receptor modulating corresponding to Formula (I):
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16. The compound of claim 16, corresponding to Formula (E2):
- 21. A method for modulating epidermal growth factor receptor (EGFR) activity comprising contacting EGFR with an effective amount of an EGFR modulating compound corresponding to Formula (I):
- 25. A method for treating a disease comprising administering to a subject in need thereof an effective amount of an epidermal growth factor receptor modulating corresponding to:
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