Transpulmonary systemic cooling using liquid mists
First Claim
Patent Images
1. A method for transpulmonary cooling, comprising the steps of:
- providing a liquid having a boiling point of 38-300°
C.;
nebulizing the liquid to form a mist; and
delivering the mist to the airway of a patient so that the patient inhales the mist to cause systemic cooling.
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Abstract
A method for transpulmonary cooling by providing a liquid having a boiling point of 38-300° C., more preferably 38-250° C., more preferably 38-200° C., more preferably 38-150° C., more preferably 38-80° C. The liquid is nebulized to form a mist. The mist is optionally cooled below room temperature and delivered to the airway of a patient so that the patient inhales the mist. The mist causes systemic cooling by evaporative heat loss when inhaled at room temperature and additionally by direct heat transfer when inhaled below room temperature. Compositions and medical devices for transpulmonary cooling are also provided.
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Citations
151 Claims
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1. A method for transpulmonary cooling, comprising the steps of:
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providing a liquid having a boiling point of 38-300°
C.;
nebulizing the liquid to form a mist; and
delivering the mist to the airway of a patient so that the patient inhales the mist to cause systemic cooling. - View Dependent Claims (2, 3, 4, 5, 6, 7, 8, 9, 10, 11, 12, 13, 14, 15, 16, 30, 31)
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17-29. -29. (canceled)
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32-63. -63. (canceled)
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64. A composition for transpulmonary cooling, comprising:
a nebulized liquid in the form of a mist, the liquid having a boiling point of 38-300°
C.
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65-111. -111. (canceled)
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112. A medical device for transpulmonary cooling, comprising:
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an inhaler device; and
a nebulized liquid in the form of a mist the liquid having a boiling point of 38-300°
C.
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113-149. -149. (canceled)
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150. A method for transpulmonary cooling, comprising the steps of:
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providing a liquid fluorocarbon;
nebulizing the liquid to form a mist;
delivering the mist to the airway of a patient so that the patient inhales the mist to cause systemic cooling;
recovering the fluorocarbon from an expired gas; and
recirculating the recovered fluorocarbon to the patient.
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151. (canceled)
Specification