Intraluminal device with a coating containing a therapeutic agent
First Claim
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1. A device, comprising:
- at least one coating containing a therapeutic agent comprised in a therapeutic matrix which covers at least a portion of the device, said therapeutic matrix disposed to deliver the therapeutic agent to tissue of a patient upon implantation in said patient, and said therapeutic matrix formed by a bio-compatible oil or fat.
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Abstract
The invention relates to an intraluminal device, in particular an intraluminal prosthesis, shunt, catheter or local drug delivery device. In order to increase the bio-compatibility of this device, it is provided with at least one coating. The coating contains a therapeutic agent which is comprised in a matrix that sticks to the intraluminal device. Instead of being formed by a little bio-compatible polymer, the matrix is formed by a bio-compatible oil or fat, such as cod-liver oil or olive oil. Preferably, the bio-compatible oil or fat further comprises alfa-tocopherol.
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Citations
39 Claims
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1. A device, comprising:
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at least one coating containing a therapeutic agent comprised in a therapeutic matrix which covers at least a portion of the device, said therapeutic matrix disposed to deliver the therapeutic agent to tissue of a patient upon implantation in said patient, and said therapeutic matrix formed by a bio-compatible oil or fat. - View Dependent Claims (2, 3, 4, 5, 6, 7, 8, 9, 10, 11, 12, 13, 14, 15, 16, 17, 18, 19, 20, 21, 22, 23, 24, 25, 29, 30, 31, 32, 33, 34, 35, 36, 37, 38, 39)
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26. A method for providing a device, comprising:
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providing said device with at least one coating containing a therapeutic agent comprised in a therapeutic matrix which covers at least a portion of the device, and applying a bio-compatible oil or fat, which comprises said therapeutic agent, in a flowable state onto the device to form said therapeutic matrix comprising the therapeutic agent. - View Dependent Claims (27, 28)
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Specification