Apparatus for measuring biological component

• US 20050159678A1
• Filed: 01/16/2004
• Published: 07/21/2005
• Est. Priority Date: 01/17/2003
• Status: Active Grant

• Current Assignee: PHC Holdings Corporation
• Original Assignee: Matsushita Electric Industrial Company Limited (Panasonic Holdings Corporation)
• Inventors: Ikeda, Shin, Yoshioka, Toshihiko, Miyashita, Mariko, Taniike, Yuko
• Granted Patent: US 7,238,160 B2
• Time in Patent Office: Days
• US Class Current: 600/583
• CPC Class Codes: A61B 5/14532 for measuring glucose, e.g. by tissue impedance measurement
• CPC Class Codes: A61B 5/150022 for capillary blood or interstitial fluid
• CPC Class Codes: A61B 5/150259 Improved gripping, e.g. with high friction pattern or projections on the housing surface or an ergonometric shape
• CPC Class Codes: A61B 5/150358 Strips for collecting blood, e.g. absorbent optical reagent test strips G01N21/8483; chemical reagent test strips G01N33/4875, G01N33/52
• CPC Class Codes: A61B 5/150412 Pointed piercing elements, e.g. needles, lancets for piercing the skin blade-like piercing elements A61B5/150442
• CPC Class Codes: A61B 5/150748 Having means for aiding positioning of the piercing device at a location where the body is to be pierced means for aiding positioning of devices for bringing media into the body A61M5/427, locating blood vessels A61B5/489
• CPC Class Codes: A61B 5/150954 Means for the detection of operative contact with patient, e.g. by temperature sensitive sensor
• CPC Class Codes: A61B 5/15107 Piercing being assisted by a triggering mechanism
• CPC Class Codes: A61B 5/15117 comprising biased elements, resilient elements or a spring, e.g. a helical spring, leaf spring, or elastic strap
• CPC Class Codes: A61B 5/15125 comprising a vacuum or compressed fluids
• CPC Class Codes: A61B 5/1519 comprising driving means, e.g. a spring, for propelling the piercing unit
• CPC Class Codes: A61B 5/157 Devices characterised by integrated means for measuring characteristics of blood
• CPC Class Codes: A61B 5/417 the bone marrow
• CPC Class Codes: A61B 5/6843 Monitoring or controlling sensor contact pressure

Abstract

The present invention relates to a biological component measurement apparatus set, in which a puncture mechanism for puncturing skin of a subject to collect a sample blood is integrated with a biosensor measurement apparatus, wherein the puncture mechanism comprises at least: a puncture needle; and a cap which is detachably engaged with a body of the apparatus, wherein the cap has a skin contact surface which is brought into contact with the skin for puncturing, the skin contact surface having an opening through which the puncture needle moves to puncture the skin, and being shaped so as to fit a surface shape of the skin to be punctured, and the set comprises a plurality of different such caps each corresponding to a different sample collection site so that a plurality of different sample collection sites can be selected.

Claims

1. A biological component measurement apparatus set,

in which a puncture mechanism for puncturing skin of a subject to collect a sample blood is integrated with a biosensor measurement apparatus,

wherein the puncture mechanism comprises at least:

a puncture needle; and

a cap which is detachably engaged with a body of the apparatus,

wherein the cap has a skin contact surface which is brought into contact with the skin for puncturing, the skin contact surface having an opening through which the puncture needle moves to puncture the skin, and being shaped so as to fit a surface shape of the skin to be punctured, and

the set comprises a plurality of different such caps each corresponding to a different sample collection site so that a plurality of different sample collection sites can be selected.

2. A biological component measurement apparatus set according to claim 1, comprising a cap for collecting a sample from a fingertip and a cap for collecting a sample from a forearm.

3. A biological component measurement apparatus set according to claim 2, further comprising a cap for collecting a sample from any site selected from the group consisting of a palm, an upper arm, a thigh, and an abdomen.

4. A biological component measurement apparatus set according to claim 1, wherein the biosensor measurement apparatus comprises:

a biological component information input member for entering measurement information from the biosensor, wherein the biological component information input member comprises a biosensor attachment member;

a sample collection site input member for entering information about the sample collection site;

a memory member;

a computing member for calculating a substrate concentration in the sample blood based on the information from the biological component information input member; and

a display member for displaying the calculated substrate concentration,

wherein the entered information about the sample collection site is stored in the memory member together with the calculated substrate concentration.

5. A biological component measurement apparatus set according to claim 4, wherein the biosensor is a glucose sensor.

6. A biological component measurement apparatus set according to claim 4, wherein the entered information about the sample collection sites is displayed on the display member together with the calculated substrate concentration.

7. A biological component measurement apparatus set according to claim 4,

wherein the cap has a pair of electric contacts placed on at least a part of a portion engaged with the body of the apparatus, the contacts being electrically connected to a constant resistance specific to the cap, and

wherein the sample collection site input member comprises a resistance measurement device and a second pair of electric contacts electrically connected to the resistance measurement device, the second pair of electric contacts being brought into contact with the pair of electric contacts to form an electric circuit such that the resistance measurement device detects the constant resistance, when the cap is engaged with the body of the apparatus,

wherein the sample collection site is recognized based on the detected value of the constant resistance.

8. A biological component measurement apparatus set according to claim 4,

wherein the biosensor measurement apparatus further comprises a mealtime input member for entering a mealtime or an elapsed time after a meal,

wherein the memory member previously has stored therein a correction table or a correction equation for correcting measurement values based on the elapsed time after a meal and the sample collection site, and

wherein the computing member refers to the correction table or the correction equation stored in the memory member, and calculates a corrected substrate concentration based on the mealtime or the elapsed time after a meal entered in the mealtime input member and the sample collection site entered in the sample collection site input member.

9. A biological component measurement apparatus,

with which a puncture mechanism for puncturing skin of a subject to collect a sample blood is integrated,

wherein the puncture mechanism comprises at least:

a puncture needle; and

a cap which is detachably engaged with a body of the apparatus,

wherein the cap has a skin contact surface which is brought into contact with the skin for puncturing, the skin contact surface having an opening through which the puncture needle moves to puncture the skin, and

the biosensor measurement apparatus comprises;

a biological component information input member for entering measurement information from the biosensor, wherein the biological component information input member comprises a biosensor attachment member;

a sample collection site input member for entering information about the sample collection site;

a computing member for calculating a substrate concentration in the sample blood based on the information from the biological component information input member;

a memory member for storing the entered information about the sample collection site together with the calculated substrate concentration; and

a display member for displaying the calculated substrate concentration,

wherein the skin contact surface of the cap comprises at least two sensors for detecting a contact with skin, which is electrically connected to the sample collection site input member when the cap is engaged with the body of the apparatus,

wherein the sample collection site input member recognizes the sample collection site based on the number and/or a combination of sensors which have detected the contact with the skin.

10. A biological component measurement apparatus according to claim 9, wherein the sample collection site input member recognizes the sample collection site as a fingertip if only a part of the sensors detect contact with the skin.

11. A biological component measurement apparatus according to claim 9, wherein the sample collection site input member recognizes the sample collection site as any site selected from the group consisting of a palm, a forearm, an upper arm, a thigh, and an abdomen, if all of the sensors detect contact with the skin.

12. A biological component measurement apparatus according to claim 9, further comprising a mealtime input member for entering a mealtime or an elapsed time after a meal,

wherein the memory member previously has stored a correction table or a correction equation for correcting the measurement values based on the elapsed time after a meal and the sample collection site, and

wherein the computing member refers to the correction table or the correction equation stored in the memory member, and calculates a corrected substrate concentration based on the mealtime or the elapsed time after a meal entered in the mealtime input member and the sample collection site entered in the sample collection site input member.

13. A biosensor measurement apparatus, comprising:

a biological component information input member for entering measurement information from the biosensor, wherein the biological component information input member comprises a biosensor attachment member;

a sample collection site input member for entering information about the sample collection site;

a computing member for calculating a substrate concentration in the sample blood based on the information from the biological component information input member;

a memory member for storing the entered information about the sample collection site together with the calculated substrate concentration; and

a display member for displaying the calculated substrate concentration.

14. A biosensor measurement apparatus according to claim 13, further comprising a mealtime input member for entering a mealtime or an elapsed time after a meal,

wherein the memory member previously has stored a correction table or a correction equation for correcting the measurement values based on the elapsed time after a meal and the sample collection site,

the computing member refers to the correction table or the correction equation stored in the memory member, and calculates a corrected substrate concentration based on the mealtime or the elapsed time after a meal entered in the mealtime input member and the sample collection site entered in the sample collection site input member,

the memory member further stores the corrected substrate concentration, and

the display member displays the corrected substrate concentration.