Interrupted, vertical flow testing device
First Claim
1. In an immunoassay flow testing device wherein a fluid specimen in a buffered solution is first contacted with a colloidal conjugate in a first part of said device, then applied to a chromatographic testing strip in a second part of said device, an improvement which comprises a flow interrupting reservoir between said first and said second parts.
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Accused Products
Abstract
In a vertical flow immunoassay testing device, the fluid specimen is deposited in a sampling well whose inclined walls and filtration material separate mucus and other adhesive matters from the more fluid components. The mixing of the specimen with a buffer solution is triggered by the closure of the device'"'"'s cap. The flow of the buffered specimen from a first chamber where it is exposed to a collodial gold conjugate to a second chamber holding a chromatographic test strip is temporarily interrupted by a holding reservoir. The specimen does not freely flow into the strip until the reservoir begins to overflow. The delay provides an incubation time for a better affinity binding of the specimen and regulates its flow through the strip.
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Citations
14 Claims
- 1. In an immunoassay flow testing device wherein a fluid specimen in a buffered solution is first contacted with a colloidal conjugate in a first part of said device, then applied to a chromatographic testing strip in a second part of said device, an improvement which comprises a flow interrupting reservoir between said first and said second parts.
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4. A flow immunoassay testing device which comprises:
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a first chamber holding a colloidal gold conjugate;
a second chamber holding at least one chromatographic testing strip; and
a flow-interrupting reservoir of a given capacity between said first and second chambers. - View Dependent Claims (5, 6, 7, 8, 9, 10, 11, 12, 13, 14)
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Specification