Vascular prosthesis including torsional stabilizer and methods of use

• US 20050165469A1
• Filed: 11/25/2003
• Published: 07/28/2005
• Est. Priority Date: 12/24/2002
• Status: Abandoned Application

• Current Assignee: NovoStent Corp.
• Original Assignee: NovoStent Corp.
• Inventors: Hogendijk, Michael
• Application Number:
  US10/723,565
• Publication Number:
  US 20050165469A1
• Time in Patent Office: Days
• US Class Current: 623/1.150
• CPC Class Codes: A61F 2/88 the wire-like elements formed as helical or spiral coils forming a net-like or mesh-like structure A61F2/90
• CPC Class Codes: A61F 2/885 comprising a coil including a plurality of spiral or helical sections with alternate directions around a central axis
• CPC Class Codes: A61F 2/91 made from perforated sheet material or tubes, e.g. perforated by laser cuts or etched holes
• CPC Class Codes: A61F 2/95 Instruments specially adapted for placement or removal of stents or stent-grafts
• CPC Class Codes: A61F 2/966 with relative longitudinal movement between outer sleeve and prosthesis, e.g. using a push rod
• CPC Class Codes: A61F 2002/068 Modifying the blood flow model, e.g. by diffuser or deflector
• CPC Class Codes: A61F 2002/828 Means for connecting a plurality of stents allowing flexibility of the whole structure
• CPC Class Codes: A61F 2220/0016 with sharp anchoring protrusions, e.g. barbs, pins, spikes
• CPC Class Codes: A61F 2230/0054 V-shaped
• CPC Class Codes: A61F 2250/0068 the pharmaceutical product being in a reservoir

Abstract

The present invention is directed to an implantable vascular prosthesis configured for use in a wide range of applications, such as treating aneurysms, maintaining patency in a vessel, and allowing for the controlled delivery of therapeutic agents to a vessel wall. The prosthesis comprises a helical proximal section coupled to a distal anchoring section having a generally zig-zag or cell-like configuration. The prosthesis is configured to conform to a vessel wall without substantially remodeling the vessel, and further is configured to be precisely deployed in a vessel without shifting during deployment. The prosthesis also has a substantially small delivery profile compared to other known stents, while having an increased surface area to enhance delivery of therapeutic agents.

Claims

1. A vascular prosthesis for implantation in a body vessel having a vessel wall, the vascular prosthesis comprising:

a proximal section comprising a plurality of helical turns and a distal end;

a distal section joined to the distal end, the distal section forming a self-expanding anchor; and

a torsional stabilizer coupled to the distal end of the proximal section.

2. The vascular prosthesis of claim 1, wherein the proximal section, distal section and torsional stabilizer each are capable of assuming a contracted state suitable for transluminal insertion into the body vessel and a deployed state wherein the proximal section, distal section and torsional stabilizer engage the vessel wall.

3. The vascular prosthesis of claim 2, wherein the distal section is configured to be deployed within the body vessel before the proximal section and torsional stabilizer are deployed.

4. The vascular prosthesis of claim 2, wherein the torsional stabilizer is configured to be deployed before the proximal section is deployed, but after the distal section is deployed.

5. The vascular prosthesis of claim 2, wherein the distal section is configured to engage the vessel wall to retain the vascular prosthesis in position during deployment of the torsional stabilizer and proximal section.

6. The vascular prosthesis of claim 1, wherein the torsional stabilizer enhances frictional engagement with the vessel wall.

7. The vascular prosthesis of claim 1, wherein the torsional stabilizer comprises a loop.

8. The vascular prosthesis of claim 1, wherein the torsional stabilizer comprises a continuation of the proximal section.

9. The vascular prosthesis of claim 1, wherein the torsional stabilizer is configured to partially overlap the distal section.

10. The vascular prosthesis of claim 1, wherein, in a fully deployed configuration, the torsional stabilizer and the distal section are oriented substantially parallel to one another.

11. The vascular prosthesis of claim 1, wherein the torsional stabilizer is biased outwardly to provide increased frictional contact with the vessel wall.

12. The vascular prosthesis of claim 1, wherein the proximal section, distal section and torsional stabilizer comprise a nickel titanium alloy.

13. The vascular prosthesis of claim 1, wherein the proximal and distal sections may be manufactured as two distinct sections, then coupled together.

14. The vascular prosthesis of claim 1, further comprising at least one through-hole disposed on a solid portion of the torsional stabilizer, the through-hole configured to contain a therapeutic agent.

15. The vascular prosthesis of claim 1, wherein the torsional stabilizer is used to orient the prosthesis axially within the body vessel.

16. A vascular prosthesis for implantation in a body vessel having a vessel wall, the vascular prosthesis including a longitudinal axis, the vascular prosthesis comprising:

a proximal section comprising a plurality of helical turns and a distal end;

a self-expanding distal section coupled to the distal end of the helical body at a junction; and

a torsional stabilizer coupled to the distal end of the proximal section.

17. The vascular prosthesis of claim 16, wherein the junction defines an origin of an X-Y coordinate system, wherein an X-axis is substantially parallel to a longitudinal axis of vascular prosthesis and a Y-axis is substantially orthogonal to the longitudinal axis of vascular prosthesis.

18. The vascular prosthesis of claim 16, wherein the torsional stabilizer extends past a plane of the X-axis.

19. The vascular prosthesis of claim 16, wherein the torsional stabilizer extends past a plane of the Y-axis.

20. The vascular prosthesis of claim 16, wherein the torsional stabilizer includes one or more radiopaque markers to facilitate alignment of the vascular prosthesis at a desired radial orientation within the vessel.