Implantable medical device

• US 20050165471A1
• Filed: 09/24/2004
• Published: 07/28/2005
• Est. Priority Date: 04/08/2003
• Status: Abandoned Application

• Current Assignee: Biophan Technologies Incorporated
• Original Assignee: Biophan Technologies Incorporated
• Inventors: Wang, Xingwu, Greenwald, Howard J.
• Application Number:
  US10/950,148
• Publication Number:
  US 20050165471A1
• Time in Patent Office: Days
• US Class Current: 623/1.150
• CPC Class Codes: A61F 2/82 Devices providing patency to, or preventing collapsing of, tubular structures of the body, e.g. stents stent-grafts for tubular structures of the body other than blood vessels A61F2/04; stent-grafts for blood vessels A61F2/07; instruments specially adapted for placement or removal of stents or stent-grafts A61F2/95; for closing wounds, or holding wounds closed A61B17/04 - A61B17/115; dilators A61M29/00
• CPC Class Codes: A61L 2300/00 Biologically active materials used in bandages, wound dressings, absorbent pads or medical devices
• CPC Class Codes: A61L 31/14 Materials characterised by their function or physical properties , e.g. injectable or lubricating compositions, shape-memory materials, surface modified materials
• CPC Class Codes: A61L 31/16 Biologically active materials, e.g. therapeutic substances A61L31/047 takes precedence
• CPC Class Codes: B82Y 15/00 Nanotechnology for interacting, sensing or actuating, e.g. quantum dots as markers in protein assays or molecular motors
• CPC Class Codes: B82Y 20/00 Nanooptics, e.g. quantum optics or photonic crystals
• CPC Class Codes: B82Y 25/00 Nanomagnetism, e.g. magnetoimpedance, anisotropic magnetoresistance, giant magnetoresistance or tunneling magnetoresistance

Abstract

A metallic stent that, when it is contacted with an input alternating current electromagnetic field and a static magnetic field that contacts biological matter located within the stent, an output signal is produced that that has a fixed phase relationship with the input signal and that has a magnitude that is at least about 0.01 times as great as the magnitude of the input signal.

Claims

1. A stent assembly comprised of a metallic stent with an interior cavity and an exterior surface, wherein biological matter is disposed within said interior cavity, wherein, when such exterior surface Is simultaneously subjected to an input alternating current electromagnetic field with a frequency of from about 1 megahertz to about 3 terahertz and a static magnetic field of from about 0.1 to about 30 Tesla, such input alternating current electromagnetic field contacts the biological matter and produces an output signal that is disposed outside of said exterior surface and that has a fixed phase relationship with the Input signal, and wherein the ratio of the magnitude of said output signal that is disposed outside of said exterior surface to the magnitude of said input alternating current electromagnetic field is at least about 0.01.

2. The stent assembly as recited in claim 1, wherein said ratio of the magnitude of said output signal that is disposed outside of said exterior surface to the magnitude of said input alternating current electromagnetic field is at least about 0.2.

3. The stent assembly as recited in claim 1, wherein said ratio of the magnitude of said output signal that is disposed outside of said exterior surface to the magnitude of said input alternating current electromagnetic field is at least about 0.3.

4. The stent assembly as recited in claim 3, wherein nanomagneuc material is disposed over said metallic stent.

5. The stent assembly as recited in claim 4, wherein said nanomagnetic material has a saturation magnetization of at least about 1.5 Tesla.

6. The stent assembly as recited in claim 5, wherein said nanomagnetic material is comprised of nanomagnetic particles with an average particle size of less than about 100 nanometers.

7. The stent assembly as recited in claim 6, wherein the average particle size of said nanomagnetic particles is from about 3 to about 10 nanometers.

8. The stent assembly as recited in claim 6, wherein said nanomagnetic particles have a coherence length of less than 100 nanometers.

9. The stent assembly as recited in claim 6, wherein said nanomagnetic material has an average particle size of less than about 20 nanometers and a phase transition temperature of less than about 200 degrees Celsius.

10. The stent assembly as recited in claim 6 wherein the average particle size of such nanomagnetic particles is less than about 15 nanometers.

11. The stent assembly as recited In claim 6, wherein said nanomagnetic material has a saturation magnetization of at least 2,500 electromagnetic units per cubic centimeter.

12. The stent assembly as recited in claim 6, wherein said particles of said nanomagnetic material have a squareness of from about 0.05 to about 1.0.

13. The stent assembly as recited in claim 6, wherein said particles of said nanomagnetic material are at least triatomic, being comprised of a first distinct atom, a second distinct atom, and a third distinct atom.

14. The stent assembly as recited in claim 13, wherein said first distinct atom is an atom selected from the group consisting of atoms of actinium, americium, berkelium, californium, cerium, chromium, cobalt, curium, dysprosium, einsteinium, erbium, europium, fermium, gadolinium, holmium, iron, lanthanum, lawrencium, lutetium, manganese, mendelevium, nickel, neodymium, neptunium, nobelium, plutonium, praseodymium, promethium, protactinium, samarium, terbium, thorium, thulium, uranium, and ytterbium, and mixtures thereof.

15. The stent assembly as recited in claim 14, wherein said first distinct atom is a cobalt atom.

16. The stent assembly as recited in claim 14, wherein said particles of nanomagnetic material are comprised of atoms of cobalt and atoms of iron.

17. The stent assembly as recited in claim 13, wherein said particles of nanomagnefic material are comprised of a said first distinct atom, said second distinct atom, said third distinct atom, and a fourth distinct atom.

18. The stent assembly as recited in claim 17, wherein said particles of nanomagnetic material are comprised of a fifth distinct atom.

19. The stent assembly as recited in claim 6, wherein said particles of nanomagnetic material have a squareness of from about 0.1 to about 0.9.

20. The stent assembly as recited in claim 6 wherein said particles of nanomagnetic material have a squareness is from about 0.2 to about 0.8.

21. The stent assembly as recited in claim 6, wherein said particles of nanomagnetic material have an average size of less of less than about 3 nanometers.

22. The stent assembly as recited in claim 6, wherein said particles of nanomagnetic material have a phase transition temperature of less than 46 degrees Celsius.

23. The stent assembly as recited in claim 6, wherein said particles of nanomagnetic material have a phase transition temperature of less than about 50 degrees Celsius.

24. The stent assembly as recited in claim 6, wherein said particles of nanomagnetic material have a coercive force of from about 0.01 to about 5,000 Oersteds.

25. The stent assembly as recited in claim 13, wherein said second distinct atom has a relative magnetic permeability of about 1.0.

26. The stent assembly as recited in claim 25, wherein said second distinct atom is an atom selected from the group consisting of aluminum, antimony, barium, beryllium, boron, bismuth, calcium, gallium, germanium, gold, indium, lead, magnesium, palladium, platinum, silicon, silver, strontium, tantalum, tin, titanium, tungsten, yttrium, zirconium, magnesium, and zinc.

27. The stent assembly as recited in claim 26, wherein said third distinct atom Is an atom selected from the group consisting of argon, bromine, carbon, chlorine, fluorine, helium, helium, hydrogen, iodine, krypton, oxygen, neon, nitrogen, phosphorus, sulfur, and xenon.

28. The stent assembly as recited in claim 27, wherein said third distinct atom Is nitrogen.

29. The stent assembly as recited in claim 6, wherein said nanomagnetic particles are comprised of atoms of oxygen.

30. The stent assembly as recited in claim 29, wherein said nanomagnetic particles are comprised of atoms of iron.

31. The stent assembly as recited in claim 30, wherein said nanomagnetic particles are comprised of atoms of cobalt.

32. The stent assembly as recited in claim 6, wherein said particles of nanomagnetic material are present in the form of a coating with a thickness of from about 400 to about 2000 nanometers.

33. The stent assembly as recited in claim 32, wherein said coating has a thickness of from about 600 to about 1200 nanometers.

34. The stent assembly as recited in claim 33, wherein said coating has a morphological density of at least about 98 percent.

35. The stent assembly as recited in claim 33, wherein said coating has a morphological density of at least about 99 percent.