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Methods for imaging the lymphatic system using dendrimer-based contrast agents

  • US 20050171424A1
  • Filed: 01/13/2004
  • Published: 08/04/2005
  • Est. Priority Date: 01/13/2004
  • Status: Abandoned Application
First Claim
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1. A method for lymphatic system imaging, comprising:

  • administering an image enhancing amount of a dendrimer conjugate to a subject, the dendrimer conjugate comprising a DAB-G4D, DAB-G5D, DAB-G6D, DAB-G7D, DAB-G8D, PAMAM-G4D, PAMAM-G5D, PAMAM-G6D, PAMAM-G7D, or PAMAM-G8D dendrimer and a metal chelate; and

    detecting a difference in an image signal intensity of at least a portion of the lymphatic system after the dendrimer conjugate is administered, wherein the difference in image signal intensity indicates a condition of the lymphatic system.

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