AFINITY DOMAIN FOR ANALYTE SENSOR
First Claim
1. A membrane suitable for use with an analyte sensor, the membrane comprising an affinity domain, wherein the affinity domain comprises a sorbent having an affinity for an interfering species.
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Abstract
Abstract of the Disclosure
The preferred embodiments provide a membrane system, particularly for use on an electrochemical sensor, wherein the membrane system includes an affinity domain that dampens the effects of target interferant(s) on the sensor. The affinity domain can be layer, surface, region, and/or portion of the membrane system formed using sorbents that have an affinity for the target interferant. The sorbents can be adapted to adsorb the interferants, for example using adsorbents such as chromatography packing materials. The sorbents can also be adapted to absorb the interferants by imprinting a molecular structure on the material that forms the affinity domain such that target interferants bind to the imprinted surfaces at the molecular level.
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18 Claims
- 1. A membrane suitable for use with an analyte sensor, the membrane comprising an affinity domain, wherein the affinity domain comprises a sorbent having an affinity for an interfering species.
- 11. An analyte sensor for measuring the concentration of an analyte in a host, the sensor comprising:
Specification