Modification of feeding behavior
First Claim
1. A method for decreasing calorie intake, food intake or appetite, or increasing energy expenditure in a subject, comprising peripherally administering a to said subject an amount of PYY effective to achieve physiological levels of PYY3-36 observed tpostprandially or an amount of a PYY agonist effective to mimic physiological levels of PYY3-36 observed postprandially, thereby decreasing the calorie intake, food intake or appetite, or increasing energy expenditure in said subject.
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Accused Products
Abstract
Methods are disclosed for decreasing calorie intake, food intake, and appetite in a subject. The methods include peripherally administering a therapeutically effective amount of PYY or an agonist thereof to the subject, thereby decreasing the calorie intake of the subject.
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Citations
104 Claims
- 1. A method for decreasing calorie intake, food intake or appetite, or increasing energy expenditure in a subject, comprising peripherally administering a to said subject an amount of PYY effective to achieve physiological levels of PYY3-36 observed tpostprandially or an amount of a PYY agonist effective to mimic physiological levels of PYY3-36 observed postprandially, thereby decreasing the calorie intake, food intake or appetite, or increasing energy expenditure in said subject.
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33. The method of claim 33, wherein peripherally administering PYY or said agonist thereof comprises administering a dose of about 10 nmol of said PYY or agonist thereof.
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47. A method for decreasing calorie intake, food intake or appetite, or increasing energy expenditure in a subject, comprising peripherally administering to said subject an amount of PYY effective to achieve physiological levels of PYY3-36 or an amount of a PYY agonist effective to mimic physiological levels of PYY3-36 thereby decreasing the calorie intake, food intake or appetite, or increasing energy expenditure in said subject.
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48-99. -99. (canceled)
- 103. A method for decreasing calorie intake, food intake or appetite in a subject, comprising peripherally administering to said subject an amount of PYY effective to achieve physiological levels of PYY3-36 observed postprandially thereby decreasing the calorie intake, food intake or appetite in said subject.
- 104. A method for decreasing calorie intake, food intake or appetite in a subject, comprising peripherally administering to said subject an amount of PYY3-36 effective to achieve physiological levels of PYY3-36 observed postprandially, thereby decreasing the calorie intake, food intake or appetite in said subject.
Specification