Ocular drug delivery
First Claim
1. A method for ocular drug delivery comprising providing to an eye of a patient a delivery device having at least one opening for release of an agent contained within at least one lumen of the device, and fixing the device to the sclera such that the agent is released into the sclera through the opening.
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Accused Products
Abstract
An ocular device that contains a drug, the device affixed to the sclera for release of drug into the sclera through at least one opening. Control of drug release may be mechanical and/or electrical, and may be at a point of use or from a remote location. In one embodiment, an electrode is affixed to the sclera opposite the device, and initiation of current releases the drug from the device via iontophoresis. The lumen or reservoir contents may be visualized, and/or an indicator may indicate content information such as volume. In one embodiment, a multicompartment device may controllably release the same drug at a different rate or different drugs at the same or different rates.
169 Citations
20 Claims
- 1. A method for ocular drug delivery comprising providing to an eye of a patient a delivery device having at least one opening for release of an agent contained within at least one lumen of the device, and fixing the device to the sclera such that the agent is released into the sclera through the opening.
- 17. An ocular drug delivery device comprising at least one lumen for containing a pharmaceutically active agent, at least one controllable opening, a subtantially linear body, the device shaped for affixing to a sclera in approximation to a conjunctiva or for locating within a tunnel created in a sclera, the device capable of controllably releasing agent contained in the lumen from the opening.
Specification