Systems and methods for removing viral agents from blood
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Accused Products
Abstract
Systems and methods treat plasma carrying contaminants and cellular matter that are capable of entraining contaminants. The systems and methods separate cellular matter from the plasma by filtration, thereby removing contaminants entrained within the cellular matter. The system and methods add to the plasma a photoactive material. The systems and methods emit radiation at a selected wavelength into the plasma to activate the photoactive material and thereby eradicate the contaminant that is free of entrainment by cellular matter.
62 Citations
69 Claims
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1-62. -62. (canceled)
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63. A method for treating plasma carrying contaminants and at least two species of cellular matter capable of entraining contaminants, the method comprising the steps of
separating a first species of cellular matter by filtration through a first filter media, thereby removing contaminants entrained within the first species of cellular matter, separating a second species of cellular matter by filtration through a second filter media, thereby removing contaminants entrained within the second species of cellular matter, adding to the plasma a photoactive material and emitting radiation at a selected wavelength into the plasma to activate the photoactive material and thereby eradicate the contaminant that is free of entrainment by cellular matter.
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64. A method for treating plasma comprising the steps of
separating from the plasma leukocytes by filtration through a first filter media, separating from the plasma platelets by filtration through a second filter media, adding to the plasma a photoactive material, and emitting radiation at a selected wavelength into the plasma to activate the photoactive material.
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65. A method for treating a plasma carrying contaminants and cellular matter capable of entraining contaminants, the method comprising the steps of
conveying plasma through a first path through a filter that separates cellular matter from the plasma, thereby removing contaminants entrained within the cellular matter, conveying the plasma from the filter through a second path that includes an attached transfer container, mixing within the transfer container the plasma with a photoactive material to form a plasma mixture, conveying a portion of the plasma mixture from the transfer container through a flush path that includes the second path to thereby expose contaminants in the second path to the photoactive material, severing the second path to separate the transfer container from the filter, the transfer container, after severance from the filter, carrying a remnant of the second path, and emitting radiation into the transfer container at a selected wavelength to activate the photoactive material in the plasma mixture and thereby eradicate the contaminant that is free of entrainment by cellular matter.
- 66. A method according to claim 66 wherein the flush path by passes the filter.
Specification