Method of stimulating/sensing brain with combination of intravascularly and non-vascularly delivered leads

• US 20050187589A1
• Filed: 02/20/2004
• Published: 08/25/2005
• Est. Priority Date: 02/20/2004
• Status: Active Grant

• Current Assignee: Boston Scientific Scimed, Inc. (Boston Scientific Corporation)
• Original Assignee: Scimed Life Systems Incorporated (Boston Scientific Corporation)
• Inventors: Garabedian, Robert J., Wallace, Michael P.
• Granted Patent: US 7,295,875 B2
• Time in Patent Office: Days
• US Class Current: 607/45
• CPC Class Codes: A61N 1/0529 Electrodes for brain stimulation
• CPC Class Codes: A61N 1/0531 Brain cortex electrodes
• CPC Class Codes: A61N 1/0534 Electrodes for deep brain stimulation
• CPC Class Codes: A61N 1/36017 with leads or electrodes penetrating the skin
• CPC Class Codes: A61N 1/36025 for treating a mental or cerebral condition
• CPC Class Codes: A61N 1/36064 Epilepsy
• CPC Class Codes: A61N 1/36067 Movement disorders, e.g. tremor or Parkinson disease stimulating motor muscle A61N1/36003
• CPC Class Codes: A61N 1/36082 Cognitive or psychiatric applications, e.g. dementia or Alzheimer's disease

Abstract

A method of treating a neurological disorder in a patient is provided. The method comprises intravascularly delivering a first electrical lead within the head of the patient, and non-vascularly delivering a second electrical lead within the head the patient. The vascular and intravascular leads are placed adjacent brain tissue (e.g., cortical brain tissue or deep brain tissue). Optionally, the method comprises implanting a source of stimulation and/or recorder within the patient'"'"'s body, and then electrically coupling the proximal ends of the electrical leads to the implanted device. Using the electrical leads, the brain tissue can then be stimulated and/or recorded in order to treat the neurological disorder.

Claims

1. A medical method performed on a patient, comprising:

intravascularly delivering a first electrical lead within the head of the patient;

non-vascularly delivering a second electrical lead within the head of the patient;

placing the first and second leads adjacent brain tissue.

2. The method of claim 1, wherein the patient has a neurological disorder, the method further comprising stimulating the brain tissue with at least one of the first and second electrical leads to treat the neurological disorder.

3. The method of claim 2, wherein the neurological disorder is a degenerative disorder.

4. The method of claim 2, wherein the neurological disorder is a brain infarction.

5. The method of claim 1, further comprising recording brain signals with at least one of the first and second electrical leads.

6. The method of claim 1, wherein the first electrical lead is introduced into the head via the circulatory system.

7. The method of claim 1, wherein the first electrical lead is introduced into the head via the ventricular system.

8. The method of claim 1, wherein the first electrical lead is placed in direct contact with the brain tissue.

9. The method of claim 1, wherein the first electrical lead is placed in indirect contact with the brain tissue.

10. The method of claim 1, wherein the first electrical lead is placed adjacent cortical brain tissue, and the second electrical lead is placed adjacent deep brain tissue.

11. The method of claim 1, wherein the first electrical lead is placed adjacent deep brain tissue, and the second electrical lead is placed adjacent cortical brain tissue.

12. The method of claim 1, wherein the first and second electrical leads are acutely placed adjacent the brain tissue.

13. The method of claim 1, wherein the first and second electrical leads are subchronically or chronically placed adjacent the brain tissue.

14. The method of claim 1, further comprising electrically connecting the electrical leads to one or more of a stimulation source and a recorder.

15. The method of claim 14, further comprising implanting the one or more stimulation source and recorder within the patient.

16. A medical method performed on a patient, comprising:

delivering a first electrical lead within the head of the patient via a blood vessel;

delivering a second electrical lead within the head of the patient via an opening in an cranium of the patient; and

placing the first and second leads adjacent brain tissue.

17. The method of claim 16, wherein the patient has a neurological disorder, the method further comprising stimulating the brain tissue with at least one of the first and second electrical leads to treat the neurological disorder.

18. The method of claim 17, wherein the neurological disorder is a degenerative disorder.

19. The method of claim 17, wherein the neurological disorder is a brain infarction.

20. The method of claim 16, further comprising recording brain signals with at least one of the first and second electrical leads.

21. The method of claim 16, wherein the first electrical lead is introduced into the head via the circulatory system.

22. The method of claim 16, wherein the first electrical lead is introduced into the head via the ventricular system.

23. The method of claim 16, wherein the first electrical lead is placed in direct contact with the brain tissue.

24. The method of claim 16, wherein the first electrical lead is placed in indirect contact with the brain tissue.

25. The method of claim 16, wherein the first electrical lead is placed adjacent cortical brain tissue, and the second electrical lead is placed adjacent deep brain tissue.

26. The method of claim 16, wherein the first electrical lead is placed adjacent deep brain tissue, and the second electrical lead is placed adjacent cortical brain tissue.

27. The method of claim 16, wherein the first and second electrical leads are acutely placed adjacent the brain tissue.

28. The method of claim 16, wherein the first and second electrical leads are subchronically or chronically placed adjacent the brain tissue.

29. The method of claim 16, further comprising electrically connecting the electrical leads to one or more of a stimulation source and a recorder.

30. The method of claim 29, further comprising implanting the one or more stimulation source and recorder within the patient.