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Methods for production of arrays with modified oligonucleotide and polynucleotide compositions

  • US 20050191655A1
  • Filed: 11/09/2004
  • Published: 09/01/2005
  • Est. Priority Date: 09/29/1999
  • Status: Abandoned Application
First Claim
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1. An array comprising a plurality of modified oligonucleotide compositions stably associated with the surface of a support, wherein each oligonucleotide composition is characterized by:

  • an oligonucleotide backbone structure modified from that of a naturally occurring nucleotide polymer;

    wherein the oligonucleotides of the composition are characterized by a binding affinity greater than that of a corresponding, non-modified oligonucleotide.

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