Non-invasive method and apparatus for determining a physiological parameter
First Claim
1. A method of determining a physiological parameter of a subject comprising:
- a) generating or detecting signals representing at least two disparate physical properties of the subject, each of said disparate physical properties having a value that varies in dependence on said physiological parameter and is independently capable of giving a measurement thereof;
b) determining the effect of changes in said physiological parameter on each of said at least two disparate physical properties; and
c) processing said signals to derive said physiological parameter from the aggregate effect of said physiological parameter on said at least two disparate physical properties.
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Abstract
The present invention relates to an apparatus and method for the non-invasive analysis of physiological attributes, such as heart rate, blood pressure, cardiac output, respiratory response, body composition, and blood chemistry analytes including glucose, lactate, hemoglobin, and oxygen saturation. Using a combination of multi-functioning disparate sensors, such as optical and electrical, improvements are made over existing physiological measurement devices and techniques. The special configuration of one or more multi-functional sensors is used to non-invasively measure multi-wavelength optical plus one or more of ECG, Bio-impedance, and RF-impedance spectroscopic data. This information is used to develop self-consistent, non-linear algorithm in order to derive the physiological attributes while compensating for various forms of interfering effects including motion artifacts, sensor attachment variability, device component variability, subject physical and physiology variability, and various interfering physiological attributes.
472 Citations
47 Claims
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1. A method of determining a physiological parameter of a subject comprising:
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a) generating or detecting signals representing at least two disparate physical properties of the subject, each of said disparate physical properties having a value that varies in dependence on said physiological parameter and is independently capable of giving a measurement thereof;
b) determining the effect of changes in said physiological parameter on each of said at least two disparate physical properties; and
c) processing said signals to derive said physiological parameter from the aggregate effect of said physiological parameter on said at least two disparate physical properties. - View Dependent Claims (2, 3, 4, 5, 6, 7, 8, 9, 10, 11, 12, 13, 14, 15, 16, 17, 18, 19)
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20. A method of determining a physiological parameter of a subject comprising:
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sensors capable of generating signals representing optical and bioelectrical properties of the subject, each of said properties having a value that varies in dependence on said physiological parameter and is independently capable of giving a measurement thereof;
determining the effect of changes in said physiological parameter on each of said optical and electrical properties; and
processing said signals to derive said physiological parameter from the aggregate effect of said physiological parameter on said optical and bioelectrical properties. - View Dependent Claims (21, 22, 23, 24)
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25. An apparatus for determining a physiological parameter of a subject comprising:
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at least two sensors for generating or detecting signals representing disparate physical properties of the subject, each of said disparate physical properties having a value that varies in dependence on said physiological parameter and is independently capable of giving a measurement thereof; and
a processor configured to process said signals to derive said physiological parameter from the aggregate effect of changes in said physiological parameter on said at least two disparate physical properties. - View Dependent Claims (26, 27, 28, 29, 30, 31, 32, 33, 34, 35, 36, 37, 38, 39, 40, 41, 42)
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43. An apparatus for determining a physiological parameter of a subject comprising:
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at least two sensors for generating or detecting signals representing optical and bioelectrical properties of the subject, each of properties having a value that varies in dependence on said physiological parameter and is independently capable of giving a measurement thereof; and
a processor configured to process said signals to derive said physiological parameter from the aggregate effect of changes in said physiological parameter on said at least optical and bioelectrical properties. - View Dependent Claims (44, 45, 46, 47)
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Specification