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Modulating a pharmacokinetic property of a drug by administering a bifunctional molecule containing the drug

  • US 20050209265A1
  • Filed: 12/13/2004
  • Published: 09/22/2005
  • Est. Priority Date: 11/19/1999
  • Status: Active Grant
First Claim
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1. A non-naturally occurring bifunctional molecule of less than about 5000 daltons consisting of a drug moiety and a pharmacokinetic modulating moiety, wherein said drug moiety and said pharmacokinetic modulating moiety are optionally joined by a linking group and said bifunctional molecule exhibits at least one modulated pharmacokinetic property upon administration to a host as compared to a free drug control.

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