Electrochemical detection method and device
First Claim
1. A device for the electrochemical detection of at least one type of a biochemical molecule—
- contained in a liquid—
from a group of predetermined biochemical molecules of different types, having a means (1) for taking up the liquid, said means having at least one reference electrode (RE) and at least one counterelectrode (GE) and also more than two working electrodes (AE1, AE2, AE3), at least in each case one working electrode (AE1, AE2, AE3) being provided for the detection of each type of a biochemical molecule, said working electrode being coated with a molecule that is complementary to the biochemical molecule to be detected, so that biochemical molecules of different types can be detected simultaneously, a potentiostat (P) for generating a predetermined voltage profile—
which is variable during the measurement—
between the working electrodes (AE1, AE2, AE3) and the reference electrode (RE), a current/voltage converter (S1, S2, S3) being connected downstream of each of the working electrodes (AE1, AE2, AE3), the current/voltage converters (S1, S2, S3) holding all of the working electrodes (AE1, AE2, AE3) at the same potential and a means (S1, S2, S3, AD) for measuring the currents flowing through the working electrodes (AE1, AE2, AE3).
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Accused Products
Abstract
The invention relates to a device for the electrochemical detection of at least one biochemical molecule—contained in a liquid—from a group of predetermined biochemical molecules, having
a means (1) for taking up the liquid, said means having at least one reference electrode (RE) and at least one counterelectrode (GE) and also a multiplicity of working electrodes (AE1, AE2, AE3), at least one working electrode (AE1, AE2, AE3) being provided for the detection of each biochemical molecule, said working electrode being coated with a molecule that is complementary to the respective biochemical molecule, so that the biochemical molecules can be detected simultaneously,
a potentiostat (P) for generating a predetermined voltage profile between the working electrodes (AE1, AE2, AE3) and the reference electrode (RE),
a current/voltage converter (S1, S2, S3) being connected downstream of each of the working electrodes (AE1, AE2, AE3), the current/voltage converters (S1, S2, S3) holding all of the working electrodes (AE1, AE2, AE3) at the same potential and
a means (Ad) for measuring the currents flowing through the working electrodes (AE1, AE2, AE3).
474 Citations
14 Claims
-
1. A device for the electrochemical detection of at least one type of a biochemical molecule—
- contained in a liquid—
from a group of predetermined biochemical molecules of different types, havinga means (1) for taking up the liquid, said means having at least one reference electrode (RE) and at least one counterelectrode (GE) and also more than two working electrodes (AE1, AE2, AE3), at least in each case one working electrode (AE1, AE2, AE3) being provided for the detection of each type of a biochemical molecule, said working electrode being coated with a molecule that is complementary to the biochemical molecule to be detected, so that biochemical molecules of different types can be detected simultaneously, a potentiostat (P) for generating a predetermined voltage profile—
which is variable during the measurement—
between the working electrodes (AE1, AE2, AE3) and the reference electrode (RE),a current/voltage converter (S1, S2, S3) being connected downstream of each of the working electrodes (AE1, AE2, AE3), the current/voltage converters (S1, S2, S3) holding all of the working electrodes (AE1, AE2, AE3) at the same potential and a means (S1, S2, S3, AD) for measuring the currents flowing through the working electrodes (AE1, AE2, AE3). - View Dependent Claims (2, 3, 4, 5, 6, 7, 8, 9, 10, 11)
- contained in a liquid—
-
12. A method for the electrochemical detection of at least one type of a biochemical molecule—
- contained in a liquid—
from a group of predetermined biochemical molecules of different types, having the following steps of;
a) providing a means (1) for taking up the liquid, the means (1) having at least one counterelectrode (GE) and a reference electrode (RE) and also more than two working electrodes (AE1, AE2, AE3), at least in each case one working electrode (AE1, AE2, AE3) being provided for the detection of each biochemical molecule, said working electrode being coated with a molecule that is complementary to the biochemical molecule to be detected, so that biochemical molecules of different types can be detected simultaneously, b) bringing the liquid into contact with the working (AE1, AE2, AE3), counter- (GE) and reference electrodes (RE), c) simultaneously applying a predetermined voltage profile—
which is variable during the measurement—
between the working electrodes (AE1, AE2, AE3) and the reference electrode (RE), andd) measuring the currents flowing through the working electrodes (AE1, AE2, AE3), all of the working electrodes (AE1, AE2, AE3) being held at the same potential during the measurement. - View Dependent Claims (14)
- contained in a liquid—
-
13. The method as claimed in claim 13, the measurement being carried out in parallel or by means of multiplexing.
Specification