Method for creating chemical sensors using contact-based microdispensing technology
First Claim
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1. A method of producing a chemical sensor, comprising:
- providing an optical array; and
contact printing one or more indicator chemistries to said optical array using one or more rigid pin printing tools, wherein said one or more indicator chemistries can optically change due to a detected ligand or analyte of interest.
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Abstract
Contact based rigid pin tool technology is utilized to print one or more indicator chemistries on an optical array or a disposable sheath configured on such arrays. Each indicator chemistry contains predetermined material, such as, light energy absorbing dye(s), optically responsive particles, etc., whose optical characteristics change in response to the target ligand or analyte. By spectrally monitoring such changes using fluorescence and/or absorption spectroscopy, detection and/or quantitation of the target ligand or analyte can be obtained.
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Citations
62 Claims
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1. A method of producing a chemical sensor, comprising:
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providing an optical array; and
contact printing one or more indicator chemistries to said optical array using one or more rigid pin printing tools, wherein said one or more indicator chemistries can optically change due to a detected ligand or analyte of interest. - View Dependent Claims (2, 3, 4, 5, 6, 7, 8, 9, 10, 11, 12, 13, 14, 15, 16, 17, 18, 19, 20, 21, 22, 23)
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24. A chemical sensor production system, comprising:
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a printing platform;
an optical array capable of being disposed within said printing platform;
one or more rigid pin printing tools adapted with said printing platform for contact printing one or more indicator chemistries on said optical array;
wherein said indicator chemistries can optically change due to a detected ligand or analyte of interest; and
a polymerization chamber arranged to polymerize said printed one or more indicator chemistries. - View Dependent Claims (25, 26, 27, 28, 29, 30, 31, 32, 33, 34, 35, 36, 37, 38, 39, 40, 41, 42, 43, 44, 54, 55, 56)
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45. A chemical sensor, comprising:
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an optical array;
one or more contact-printed indicator chemistries arranged on said optical array;
wherein said indicator chemistries can optically change due to a detected ligand or analyte of interest. - View Dependent Claims (46, 47, 48, 49, 50, 51, 52, 53, 57, 58, 59, 60, 61, 62)
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Specification