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Combination of zd6474, an inhibitor of the vascular endothelial growth factor receptor, with radiotherapy in the treatment of cancer

  • US 20050222183A1
  • Filed: 08/05/2003
  • Published: 10/06/2005
  • Est. Priority Date: 08/09/2002
  • Status: Abandoned Application
First Claim
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1. A method for the production of an antiangiogenic and/or vascular permeability reducing effect in a warm-blooded animal, which comprises administering to said animal an effective amount of 4-(4-bromo-2-fluoroanilino)-6-methoxy-7-(1-methylpiperidin-4-ylmethoxy)quinazoline, also known as ZD6474:

  • embedded image or a pharmaceutically acceptable salt thereof, before, after or simultaneously with an effective amount of ionising radiation.

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