Device including a proteinaceous factor, a recombinant proteinaceous factor, and a nucleotide sequence encoding the proteinaceous factor
First Claim
1. A device including a proteinaceous factor encoded by the nucleotide sequence of any one of SEQ ID NO.:
- 1, a degenerate variant of SEQ ID NO.;
1, and a complement of SEQ ID NO.;
1.
1 Assignment
0 Petitions
Accused Products
Abstract
A device that includes a proteinaceous factor is disclosed. The proteinaceous factor is encoded by the nucleotide sequence of any one of SEQ ID NO.: 1, a degenerate variant of SEQ ID NO.: 1, and a complement of SEQ ID NO.: 1. The proteinaceous factor may be a recombinant. In addition, the device may include any one of (i) Immunoglobulin G (IgG) bound non-specially to the proteinaceous factor, (ii) at least one diagnostic label bound to the proteinaceous factor, (iii) Immunoglobulin G bound non-specially to the proteinaceous factor and at least one diagnostic label bound to the proteinaceous factor, and (iv) at least one base supporting the proteinaceous factor.
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Citations
117 Claims
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1. A device including a proteinaceous factor encoded by the nucleotide sequence of any one of SEQ ID NO.:
- 1, a degenerate variant of SEQ ID NO.;
1, and a complement of SEQ ID NO.;
1. - View Dependent Claims (2, 3, 4, 5, 6, 7, 8, 9, 10, 11, 12, 13, 14, 15, 16, 17, 18, 19, 20, 21, 22, 23, 24, 25, 26, 27, 28)
- 1, a degenerate variant of SEQ ID NO.;
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29. A recombinant proteinaceous factor usable alone or in a device, the recombinant proteinaceous factor encoded by the nucleotide sequence of any one of SEQ ID NO.:
- 1, a degenerate variant of SEQ ID NO.;
1, and a complement of SEQ ID NO.;
1. - View Dependent Claims (30, 31, 32, 33, 34, 35, 36, 37, 38, 39, 40, 41, 42, 43, 44, 45, 46, 47, 48, 49)
- 1, a degenerate variant of SEQ ID NO.;
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50. A device including:
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(a) a recombinant proteinaceous factor encoded by the nucleotide sequence of any one of SEQ ID NO.;
1, a degenerate variant of SEQ ID NO.;
1, and a complement of SEQ ID NO.;
1; and
(b) at least one of;
(i) Immunoglobulin G (IgG) bound non-specially to the proteinaceous factor;
(ii) at least one diagnostic label bond to the proteinaceous factor;
(iii) Immunoglobulin G bound non-specially to the proteinaceous factor and at least one diagnostic label to the proteinaceous factor; and
(iv) at least one base supporting the proteinaceous factor. - View Dependent Claims (51, 52, 53, 54, 55, 56, 57, 58, 59, 60, 61, 62, 63, 64, 65, 66, 67, 68, 69, 70, 71, 72, 73, 74, 75, 76, 77, 78, 79, 80, 81, 82, 83, 84, 85, 86, 87, 88, 89, 90, 91, 92, 93, 94, 95, 96)
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97. An isolated DNA the nucleotide sequence of which consists of SEQ ID NO.:
- 1.
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98. An isolated nucleic acid comprising the nucleotide sequence of SEQ ID NO.:
- 1, or a degenerate variant of SEQ ID NO.;
1. - View Dependent Claims (106, 107, 108, 109, 110, 111)
- 1, or a degenerate variant of SEQ ID NO.;
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99. An isolated nucleic acid comprising a sequence that encodes a proteinaceous factor with the amino acid sequence of SEQ ID NO.:
- 2.
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100. An isolated nucleic acid comprising a sequence that hybridizes under highly stringent conditions to a hybridization probe, the nucleotide sequence of which consists of SEQ ID NO.:
- 1, or the complement of SEQ ID NO.;
1.
- 1, or the complement of SEQ ID NO.;
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101. An isolated nucleic acid comprising a sequence at least 80% identical to SEQ ID NO.:
- 1.
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102. An isolated nucleic acid comprising a sequence that encodes a proteinaceous factor, the amino acid sequence of which is at least 80% identical to SEQ ID NO.:
- 2.
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103. An isolated nucleic acid comprising a sequence that encodes a proteinaceous factor having the sequence of SEQ ID NO.:
- 2, or SEQ ID NO.;
2 with conservative amino acid substitutions.
- 2, or SEQ ID NO.;
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104. An isolated nucleic acid comprising a sequence that encodes a polypeptide comprising the amino acid sequence of SEQ ID NO.:
- 2, or of a fragment of SEQ ID NO.;
2 at least 8 residues in length.
- 2, or of a fragment of SEQ ID NO.;
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105. A DNA the sequence of which comprises SEQ ID NO.:
- 1 operably linked to a heterologous coding sequence.
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112. A single-stranded nucleic acid that hybridizes under highly stringent conditions to a nucleic acid having the sequence of SEQ ID NO.:
- 1.
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113. An isolated nucleic acid comprising at least 10 consecutive nucleotides of the complement of SEQ ID NO.:
- 1.
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114. A purified proteinaceous factor, the amino acid sequence of which consists of SEQ ID NO.:
- 2.
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115. A method for making a device, the method comprising providing a proteinaceous factor encoded by the nucleotide sequence of any one of SEQ ID NO.:
- 1, a degenerate variant of SEQ ID NO.;
1, and a complement of SEQ ID NO.;
1.
- 1, a degenerate variant of SEQ ID NO.;
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116. A method for making a recombinant proteinaceous factor usable alone or in a device, the method comprising transforming a vector including any one of SEQ ID NO.:
- 1, a degenerate variant of SEQ ID NO.;
1, and a complement of SEQ ID NO.;
1 into a host to express the recombinant proteinaceous factor encoded thereby.
- 1, a degenerate variant of SEQ ID NO.;
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117. A method for making a device, the method comprising:
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(a) providing a recombinant proteinaceous factor encoded by the nucleotide sequence of any one of SEQ ID NO.;
1, a degenerate variant of SEQ ID NO.;
1, and a complement of SEQ ID NO.;
1; and
(b) performing at least one of;
(i) binding at least one substrate of the proteinaceous factor to the proteinaceous factor;
(ii) binding at least one chemical conjugate of the proteinaceous factor to the proteinaceous factor, (iii) binding at least one substrate of the proteinaceous factor and at least one chemical conjugate of the proteinaceous factor bond to the proteinaceous factor, and (iv) providing at least one base to support the proteinaceous factor.
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Specification