Isolating and quantifying functional impairments of the gaze stabilization system

• US 20050243277A1
• Filed: 04/28/2005
• Published: 11/03/2005
• Est. Priority Date: 04/28/2004
• Status: Active Grant

• Current Assignee: Natus Medical Incorporated
• Original Assignee: Neurocom International Inc. (Natus Medical Incorporated)
• Inventors: Nashner, Lewis M.
• Granted Patent: US 7,195,355 B2
• Time in Patent Office: Days
• US Class Current: 351/246
• CPC Class Codes: A61B 3/028 for testing visual acuity; for determination of refraction, e.g. phoropters
• CPC Class Codes: A61B 3/113 for determining or recording eye movement
• CPC Class Codes: A61B 5/11 Measuring movement of the entire body or parts thereof, e.g. head or hand tremor, mobility of a limb for measuring pulse A61B5/02 ;A61B5/1038 takes precedence; motion detection to correct for motion artifacts in physiological signals A61B5/721

Abstract

A method for isolating and quantifying impairments of a subject'"'"'s gaze stabilization system is provided. A subject'"'"'s static visual acuity is measured to arrive at an assessment. The subject'"'"'s visual acuity is then measured when the subject'"'"'s head is moving and a display object is fixed to arrive at a first dynamic measurement. The subject'"'"'s visual acuity is also measured when the subject'"'"'s head is fixed and the display object is moving to arrive at a second dynamic measurement. The assessment and the first and second dynamic measurements are then used to determine an impairment of the subject'"'"'s gaze stabilization system.

Claims

1. A method for isolating and quantifying impairments of a subject'"'"'s gaze stabilization system, the method comprising:

measuring the subject'"'"'s static visual acuity to arrive at an assessment;

measuring the subject'"'"'s visual acuity when the subject'"'"'s head is moving and a display object is fixed to arrive at a first dynamic measurement;

measuring the subject'"'"'s visual acuity when the subject'"'"'s head is fixed and the display object is moving to arrive at a second dynamic measurement;

using the assessment and the first and second dynamic measurements to determine an impairment of the subject'"'"'s gaze stabilization system.

2. A method according to claim 1, wherein measuring the subject'"'"'s static visual acuity to arrive at an assessment includes using the assessment to set parameters for a performance of a task by the subject.

3. A method according to claim 1, further comprising:

measuring the subject'"'"'s visual acuity when the subject'"'"'s head is fixed and the display object is discontinuously moving to arrive at a third dynamic measurement; and

using the assessment and the first, second and third dynamic measurement to determine impairment of the subject'"'"'s gaze stabilization system.

4. A method according to claim 1, further comprising:

measuring the subject'"'"'s visual acuity when the subject'"'"'s head is fixed, the display object is moving, and a patterned large field background is moving to arrive at a fourth dynamic measurement to determine impairment of the subject'"'"'s gaze stabilization system.

5. A method according to claim 1, wherein assessing the subject'"'"'s static visual acuity includes determining a smallest object that the subject can identify during a plurality of trials.

6. A method according to claim 1, wherein measuring the subject'"'"'s visual acuity when the subject'"'"'s head is moving and the display object is fixed includes:

fixing the size of the display object in relation to the subject'"'"'s static visual acuity;

fixing the duration that the display object is displayed to between 40 and 100 milliseconds; and

determining the maximum head movement velocity during which the subject can correctly identify the display object over a plurality of trials.

7. A method according to claim 1, wherein measuring the subject'"'"'s visual acuity when the subject'"'"'s head is fixed and the display object is continuously moving includes:

fixing the size of the display object in relation to the subject'"'"'s static visual acuity; and

fixing the duration that the display object is displayed to between 40 and 100 milliseconds; and

determining the maximum display object movement velocity during which the subject can correctly identify the display object over a plurality of trials.

8. A method according to either of claims 6 or 7, wherein the display object is displayed for approximately 75 milliseconds.

9. A method according to claim 1, wherein measuring the subject'"'"'s visual acuity when the subject'"'"'s head is fixed and the display object is continuously moving includes:

displaying a patterned large field background; and

moving the patterned large field background.

10. A method according to claim 3, wherein measuring the subject'"'"'s visual acuity when the subject'"'"'s head is fixed and the display object is discontinuously moving includes:

fixing the size of the display object in relation to the subject'"'"'s static visual acuity;

fixing the duration that the display object is displayed to about 90 milliseconds;

causing the subject to direct gaze towards a central marker for between 40 and 100 milliseconds;

causing the display object to appear at a predetermined location relative to the central marker; and

determining the maximum distance from the central marker during which the subject can correctly identify the display object over a plurality of trials.

11. A method according to claim 10, wherein the subject is caused to direct gaze toward a central marker for approximately 75 milliseconds.

12. A method according to claim 10, wherein causing the display object to appear at a predetermined location relative to the central marker includes causing the display object to appear at a fixed distance from the central marker.

13. A method according to claim 10, wherein causing the display object to appear at a predetermined location relative to the central marker includes causing the display object to appear at various directions from the central marker.

14. A method according to claim 1, wherein measuring the subject'"'"'s static visual acuity includes using a Snellen eye chart.

15. A method according to claim 1, wherein measuring the subject'"'"'s static visual acuity includes using a Tumpling E chart.

16. A method according to claim 1, further comprising:

directing the subject to perform at least one free standing balance task while measuring the subject'"'"'s visual acuity.

17. A method according to claim 16, wherein directing the subject to perform at least one free standing balance task includes directing the subject to stand on at least one surface which moves in relation to display of the display object.

18. A method according to claim 17, further comprising:

moving a patterned large field background in relation to the movement of the surface.

19. A method according to claim 17, wherein the surface moves discontinuously in relation to display of the display object.

20. A method according to any of claims 16, 17, or 18, wherein the surface is a force plate.

21. A method according to any of claims 16, 17 or 18, wherein the surface is a treadmill.

22. A method according to claim 21, wherein velocity associated with the treadmill is constant.

23. A method according to claim 21, wherein velocity associated with the treadmill is caused to vary.

24. A method according to claim 16, 17 or 18, wherein directing the subject to perform at least one free standing balance task includes directing the subject to perform at least one free standing balance task while surrounded by a visual surround.

26. A method according to either of claims 14 or 15, wherein measuring aspects of the subject'"'"'s dynamic visual acuity includes measuring aspects of the subject'"'"'s dynamic visual acuity related to two or more of:

the subject'"'"'s vestibule-ocular reflex system;

the subject'"'"'s smooth pursuit eye movement system;

the subject'"'"'s optokinetic eye movement system; and

the subject'"'"'s saccadic movement system.

27. A method according to claim 26, further comprising:

calculating a second quantity related to the subject'"'"'s static visual acuity and a second aspect of the subject'"'"'s dynamic visual acuity;

comparing the second quantity with a normative value similarly derived from a population of individuals free of gaze stabilization impairments; and

determining a second impairment of the subject'"'"'s gaze stabilization system when the third quantity varies from the normative value by more than one standard deviation

25. A method for isolating and quantifying impairments of a subject'"'"'s gaze stabilization system, the method comprising:

assessing the subject'"'"'s static visual acuity;

measuring at least two aspects of the subject'"'"'s dynamic visual acuity;

calculating a first quantity related to both the subject'"'"'s static visual acuity and a first aspect of the subject'"'"'s dynamic visual acuity;

comparing the first quantity with a normative value similarly derived from a population of individuals free of gaze stabilization impairments; and

and determining an impairment of the subject'"'"'s gaze stabilization system when the first quantity varies from the normative value by more than one standard deviation.

28. A method for isolating and quantifying impairments of a subject'"'"'s gaze stabilization system, the method comprising:

assessing the subject'"'"'s static visual acuity;

measuring the subject'"'"'s visual acuity when the subject'"'"'s head is moving and a display object is fixed to determine a first relationship to the subject'"'"'s static visual acuity;

measuring the subject'"'"'s visual acuity when the subject'"'"'s head is fixed and the display object is continuously moving to determine a second relationship to the subject'"'"'s static visual acuity;

measuring the subject'"'"'s visual acuity when the subject'"'"'s head is fixed and the display object is discontinuously moving to determine a third relationship to subject'"'"'s static visual acuity;

measuring the subject'"'"'s visual acuity when the subject'"'"'s head is fixed, the display object is continuously moving, and the patterned large field background is continuously moving to determine a fourth relationship to the subject'"'"'s static visual acuity; and

determining the extent to which impairments of the subject'"'"'s gaze stabilization system reduce the subject'"'"'s ability to perceive objects based on the first, second, third, and fourth relationships.

29. A method for isolating and quantifying impairments of a subject'"'"'s gaze stabilization system, the method comprising:

measuring the subject'"'"'s static visual acuity to arrive at an assessment;

measuring the subject'"'"'s visual acuity when the subject is standing on a continuously moving support surface, the subject'"'"'s head is moving a display object is fixed to arrive at a first dynamic measurement;

measuring the subject'"'"'s visual acuity when the subjects is standing on the continuously moving support surface, the subject'"'"'s head is fixed and the display object is moving to arrive at a second dynamic measurement;

using the assessment and the first and second dynamic measurements to determine an impairment of the subject'"'"'s gaze stabilization system.

30. A method for isolating and quantifying impairments of a subject'"'"'s gaze stabilization system, the method comprising:

measuring the subject'"'"'s static visual acuity to arrive at an assessment;

measuring the subject'"'"'s visual acuity when the subject is standing on a support surface that is discontinuously moving, the subject'"'"'s head is moving a display object is fixed to arrive at a first dynamic measurement;

measuring the subject'"'"'s visual acuity when the subjects is standing on the support surface that is discontinuously moving, the subject'"'"'s head is fixed and the display object is moving to arrive at a second dynamic measurement;

using the assessment and the first and second dynamic measurements to determine an impairment of the subject'"'"'s gaze stabilization system.