Combination lead for electrical stimulation and sensing

• US 20050246004A1
• Filed: 04/28/2005
• Published: 11/03/2005
• Est. Priority Date: 04/28/2004
• Status: Abandoned Application

• Current Assignee: Advanced Neuromodulation Systems Incorporated (Abbott Laboratories Incorporated)
• Original Assignee: Advanced Neuromodulation Systems Incorporated (Abbott Laboratories Incorporated)
• Inventors: Daglow, Terry D., Cameron, Tracy L., Black, Damon R.
• Application Number:
  US11/116,557
• Publication Number:
  US 20050246004A1
• Time in Patent Office: Days
• US Class Current: 607/116
• CPC Class Codes: A61N 1/0529 Electrodes for brain stimulation
• CPC Class Codes: A61N 1/0539 Anchoring of brain electrode systems, e.g. within burr hole
• CPC Class Codes: A61N 1/0553 Paddle shaped electrodes, e.g. for laminotomy

Abstract

In one embodiment, an electrical stimulation lead is adapted for implantation in a person'"'"'s body to provide therapeutic electrical stimulation of target nerve tissue within the person'"'"'s body. The stimulation lead includes one or more stimulating electrodes and one or more sensing electrodes integrated into the stimulation lead and adapted for implantation in the person'"'"'s body with the stimulation lead. The stimulating electrodes are operable to provide electrical stimulation to target nerve tissue within the person'"'"'s body. The sensing electrodes are operable to detect electrical signals produced by nerve cells within the person'"'"'s body to facilitate precise positioning of the stimulating electrodes proximate the target nerve tissue during implantation of the stimulation lead.

Claims

1. An electrical stimulation lead adapted for implantation in a person'"'"'s body to provide therapeutic electrical stimulation of target nerve tissue within the person'"'"'s body, comprising:

one or more stimulating electrodes integrated into the stimulation lead, adapted for implantation in the person'"'"'s body with the stimulation lead, and operable to provide electrical stimulation to target nerve tissue within the person'"'"'s body; and

one or more sensing electrodes integrated into the stimulation lead, adapted for implantation in the person'"'"'s body with the stimulation lead, and operable to detect electrical signals produced by nerve cells within the person'"'"'s body to facilitate precise positioning of the one or more stimulating electrodes proximate the target nerve tissue during implantation of the stimulation lead.

2. The stimulation lead of claim 1, wherein:

the stimulation lead is adapted to be coupled to a monitoring system; and

the one or more sensing electrodes are operable to transmit signals reflecting

the detected electrical signals to the monitoring system for determination of the precise location of the one or more sensing electrodes within the person'"'"'s body based at least on the signals reflecting the detected electrical signals.

3. The stimulation lead of claim 1, wherein:

each sensing electrode is a semi-microelectrode; and

each stimulating electrode is a macroelectrode.

4. The stimulation lead of claim 1, wherein:

the stimulation lead is a percutaneous lead;

the one or more stimulating electrodes comprise a plurality of circumferential electrodes spaced apart from each other along a length of a stimulating portion of the stimulation lead; and

the one or more sensing electrodes comprise a plurality of electrodes spaced apart from one another around the circumference of the stimulation lead at its tip.

5. The stimulation lead of claim 1, wherein:

the stimulation lead is a percutaneous lead;

the one or more stimulating electrodes comprise a plurality of circumferential electrodes spaced apart from each other along a length of a stimulating portion of the stimulation lead; and

the one or more sensing electrodes comprise a plurality of electrodes spaced apart from one another around the circumference of the stimulation lead between two of the plurality of stimulation electrodes.

6. The stimulation lead of claim 1, wherein:

the stimulation lead is a paddle lead;

the one or more sensing electrodes are directional electrodes located on a surface of the stimulation lead and adapted to detect electrical signals produced by nerve cells within the person'"'"'s body in a direction generally perpendicular to the surface of stimulation lead; and

the one or more stimulating electrodes are directional electrodes located on the surface of the stimulation lead and adapted to deliver electrical energy to the target nerve tissue in a direction generally perpendicular to the surface of stimulation lead.

7. The stimulation lead of claim 1, wherein the electrodes are separated from each other by one or more dielectric materials.

8. The stimulation lead of claim 1, wherein the target nerve tissue comprises one of:

brain stem tissue;

spinal cord tissue; and

peripheral nerve tissue.

9. A stimulation system for providing therapeutic electrical stimulation to target nerve tissue in a person'"'"'s body, comprising:

a stimulation source operable to generate and transmit electrical stimulation pulses;

an electrical stimulation lead adapted for implantation into a person'"'"'s body for electrical stimulation of target nerve tissue within the person'"'"'s body, the stimulation lead comprising;

one or more stimulating electrodes integrated into the stimulation lead, adapted for implantation in the person'"'"'s body with the stimulation lead, and operable to deliver the electrical stimulation pulses to target nerve tissue within the person'"'"'s body to provide therapeutic relief to a region of the person'"'"'s body corresponding to the target nerve tissue; and

one or more sensing electrodes integrated into the stimulation lead, adapted for implantation in the person'"'"'s body with the stimulation lead, and operable to detect electrical signals produced by nerve cells within the person'"'"'s body to facilitate precise positioning of the one or more stimulating electrodes proximate the target nerve tissue during implantation of the stimulation lead.

10. The system of claim 9, operable to transmit signals reflecting the detected electrical signals to a monitoring system for determination of the precise location of the one or more sensing electrodes within the person'"'"'s body based at least on the signals reflecting the detected electrical signals.

11. The system of claim 10, wherein the monitoring system comprises a computer system external to the person'"'"'s body.

12. The system of claim 11, wherein the monitoring system is further operable to control one or more stimulation parameters of the electrical stimulation pulses generated by the stimulation source based at least on the received signals reflecting the detected electrical signals.

13. The system of claim 11, wherein the monitoring system is further operable to cause the stimulation source to begin generating electrical stimulation pulses based at least on the received signals reflecting the detected electrical signals.

14. The system of claim 9, wherein:

each sensing electrode is a semi-microelectrode; and

each stimulating electrode is a macroelectrode.

15. The system of claim 9, wherein:

the stimulation lead is a percutaneous lead;

the one or more stimulating electrodes comprise a plurality of circumferential electrodes spaced apart from each other along a length of a stimulating portion of the stimulation lead; and

the one or more sensing electrodes comprise a plurality of electrodes spaced apart from one another around the circumference of the stimulation lead at its tip.

16. The system of claim 9, wherein:

the stimulation lead is a percutaneous lead;

the one or more stimulating electrodes comprise a plurality of circumferential electrodes spaced apart from each other along a length of a stimulating portion of the stimulation lead; and

the one or more sensing electrodes comprise a plurality of electrodes spaced apart from one another around the circumference of the stimulation lead and between two of the plurality of stimulation electrodes.

17. The system of claim 9, wherein:

the stimulation lead is a paddle lead;

the one or more sensing electrodes are directional electrodes located on a surface of the stimulation lead and adapted to detect electrical signals produced by nerve tissue within the person'"'"'s body in a direction generally perpendicular to the surface of stimulation lead; and

the one or more stimulating electrodes are directional electrodes located on the surface of the stimulation lead and adapted to deliver electrical energy to the target nerve tissue in a direction generally perpendicular to the surface of stimulation lead.

18. The system of claim 9, wherein the target nerve tissue comprises one of:

brain stem tissue;

spinal cord tissue; and

peripheral nerve tissue.

19. A percutaneous stimulation lead adapted for implantation in a person'"'"'s body to provide therapeutic electrical stimulation of target nerve tissue within the person'"'"'s body, comprising:

a plurality of circumferential stimulating electrodes integrated into the stimulation lead, spaced apart from each other along a length of a stimulating portion of the stimulation lead, separated from each other by one or more dielectric materials, adapted for implantation in the person'"'"'s body with the stimulation lead, and operable to provide electrical stimulation to target nerve tissue within the person'"'"'s body; and

one or more sensing electrodes integrated into the stimulation lead, spaced apart from one another around the circumference of the stimulation lead at its tip, separated from each other by one or more dielectric materials, adapted for implantation in the person'"'"'s body with the stimulation lead, and operable to detect electrical signals produced by nerve cells within the person'"'"'s body to facilitate precise positioning of the one or more stimulating electrodes proximate the target nerve tissue during implantation of the stimulation lead;

the stimulation lead adapted to be coupled to a monitoring system, the one or more sensing electrodes being operable to transmit signals reflecting the detected electrical signals to the monitoring system for determination of the precise location of the one or more sensing electrodes within the person'"'"'s body based at least on the signals reflecting the detected electrical signals.

20. The stimulation lead of claim 19, wherein the target nerve tissue comprises one of:

brain stem tissue;

spinal cord tissue; and

peripheral nerve tissue.