Multiple drug delivery from a balloon and a prosthesis
First Claim
1. A system for delivering a beneficial agent, comprising:
- a) a balloon having an outer surface that is at least partially coated with a therapeutically effective amount of a first beneficial agent; and
b) a prosthesis that can be delivered or implanted having a surface that is at least partially coated with a therapeutically effective amount of a second beneficial agent wherein the system is useful for the treatment and prevention of vascular diseases.
1 Assignment
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Accused Products
Abstract
Disclosed is an interventional device for delivery of therapeutic agents from an angioplasty balloon and from a prosthesis such as an intraluminal stent. The invention also relates to the method of loading the beneficial agents onto the balloon and the device, as well as the method of delivery of the agents from separate surfaces. The invention also relates to an interventional device having a prosthesis surface that is loaded with a first beneficial agent, and a balloon surface loaded with a second beneficial agent. The invention also relates to a method of loading multiple beneficial agents onto the prosthesis surfaces and the balloon surfaces, and to a method of manufacturing an interventional device for the delivery of a first beneficial agent and a second beneficial agent from separate surfaces.
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Citations
66 Claims
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1. A system for delivering a beneficial agent, comprising:
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a) a balloon having an outer surface that is at least partially coated with a therapeutically effective amount of a first beneficial agent; and
b) a prosthesis that can be delivered or implanted having a surface that is at least partially coated with a therapeutically effective amount of a second beneficial agent wherein the system is useful for the treatment and prevention of vascular diseases. - View Dependent Claims (2, 3, 4, 5, 6, 7, 8, 9, 10, 11, 12, 13, 14, 15, 16, 17, 18, 19, 20, 21, 22, 23, 24, 25, 26, 27, 28, 29, 30, 31, 50)
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40. A method of treating and preventing a vascular disease, comprising the steps of:
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a) delivering a balloon having an outer surface that is at least partially coated with a therapeutically effective amount of a first beneficial agent; and
b) delivering a prosthesis having a surface that is at least partially coated with a therapeutically effective amount of a second beneficial agent. - View Dependent Claims (41, 42, 43, 44, 45, 46, 47, 48, 49)
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60. A method of providing a device for treatment and prevention of vascular disease, comprising the steps of:
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a) providing a beneficial agent; and
b) coating said beneficial agent onto said balloon. - View Dependent Claims (61, 62, 63, 64, 65, 66)
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Specification