Analytical systems, devices, and cartridges therefor
First Claim
1. A cartridge comprising at least two test sites having at least two test site read zones for the detection or quantification of at least two different analytes and configured to use at least two different techniques for the detection or quantification of the at least two different analytes, wherein the location of at least one of the at least two test site read zones is not dependent on a corresponding measurement device.
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Accused Products
Abstract
Described here are systems, devices, cartridges, methods, and kits for detecting or quantifying at least two different analytes using at least two different techniques, in a single sample. The cartridges typically comprise at least two test sites and the location of at least one test site is not dependent on a corresponding measurement device. The systems generally comprise a device, memory, and a processing module. The device comprises a light source, an array detector, and a port configured to accept at least a portion of a cartridge. The processing module is configured to perform an image analysis of the cartridge. The methods comprise the steps of acquiring calibration information, acquiring an image of the cartridge, performing an image analysis, and cycling through specific detection or quantification techniques corresponding to the techniques required by the test sites. Computer readable media are also described.
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Citations
76 Claims
- 1. A cartridge comprising at least two test sites having at least two test site read zones for the detection or quantification of at least two different analytes and configured to use at least two different techniques for the detection or quantification of the at least two different analytes, wherein the location of at least one of the at least two test site read zones is not dependent on a corresponding measurement device.
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18. A cartridge comprising:
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a bottom layer, wherein, at least a portion of the bottom layer is non-porous;
a sample distribution layer; and
at least two test sites having at least two test site read zones;
wherein the test sites are adjacent to or embedded within the sample distribution layer and configured to detect at least two analytes using two different techniques, and wherein the location of at least one of the at least two test site read zones is not dependent on a corresponding measurement device. - View Dependent Claims (19, 20, 21, 22, 23, 24, 25, 26, 27, 28, 29, 30, 31, 32, 33, 34, 35, 36, 37)
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38. A system for detecting or quantifying at least two different analytes comprising:
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a device, wherein the device comprises a port configured to accept at least a portion of a cartridge, the cartridge having at least two test site read zones and the portion having at least one test site read zone, a light source, and an array detector;
memory; and
a processing module configured to receive signals from the array detector and to perform an image analysis of the cartridge to identify the location of at least one of the test site read zones, wherein the system enables the detection or quantification of the at least two analytes using at least two different detection or quantification techniques. - View Dependent Claims (39, 40, 41, 42, 43, 44, 45, 46, 47, 48, 49, 50, 51)
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52. A device for detecting or quantifying at least two different analytes comprising:
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a port configured to accept at least a portion of a cartridge, the cartridge having at least two test site read zones and the portion thereof having at least one test site read zone;
a light source;
an array detector;
memory; and
a processing module configured to receive signals from the array detector and to perform an image analysis of the cartridge to identify the location of at least one of the test site read zones, wherein the device enables the detection or quantification of the at least two analytes using at least two different detection or quantification techniques. - View Dependent Claims (53, 54, 55, 56, 57, 58, 59, 60, 61, 62, 63)
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- 64. A computer readable medium containing code for performing an image analysis of a cartridge comprising at least two test site read zones for the detection or quantification of at least two different analytes and configured to use at least two different techniques for the detection or quantification of the at least two different analytes, wherein the image analysis identifies the location of at least one of the test site read zones.
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67. A method for detecting or quantifying at least two different analytes on a single cartridge using at least two different detection or quantification techniques comprising the steps of:
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acquiring calibration information for a cartridge having at least two test site read zones;
acquiring an image of the cartridge using an array detector;
performing an image analysis of the cartridge to identify the location of at least one of the test site read zones; and
cycling through specific detection or quantification techniques corresponding to the detection or quantification techniques required by the test site read zones, wherein at least two different techniques are used.
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68. A device for detecting or quantifying analytes comprising:
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a port configured to accept at least a portion of a cartridge, the portion having at least one test site read zone; and
a processing module, wherein the processing module is automatically upgradeable. - View Dependent Claims (69, 70, 71, 72, 73, 74, 75)
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76. A method for detecting or quantifying at least one analyte comprising the steps of:
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providing a device comprising a port configured to accept at least a portion of a cartridge, the portion having at least one test site read zone, and a processing module, wherein the processing module is automatically upgradeable;
allowing the processing module to be automatically upgraded; and
using the upgraded processing module to calculate at least one test result.
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Specification