Bone substitute compositions and method of use
First Claim
Patent Images
1. A composition comprising:
- a mineral component that hardens in an aqueous environment; and
a non-aqueous component having an aqueous replacement characteristic that causes the composition to harden when replaced with aqueous body fluid.
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Abstract
The present invention relates to novel bone substitute compositions and methods of use. It further encompasses the use of these novel bone substitute compositions for bone augmentation and the treatment of disease conditions. The invention also contemplates a kit including bone substitute compositions and a percutaneous delivery device.
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Citations
28 Claims
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1. A composition comprising:
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a mineral component that hardens in an aqueous environment; and
a non-aqueous component having an aqueous replacement characteristic that causes the composition to harden when replaced with aqueous body fluid. - View Dependent Claims (2, 3, 4, 5, 6, 7, 8, 18, 19, 20, 22, 23, 24, 25, 26, 27, 28)
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9. A composition comprising:
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calcium sulfate-anhydrous;
calcium sulfate-dihydrate; and
polyethylene glycol (PEG). - View Dependent Claims (10, 11, 12, 13, 14, 15)
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16. A composition comprising:
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calcium sulfate-anhydrous;
calcium sulfate α
-hemihydrate;
calcium sulfate-dihydrate; and
polyethylene glycol (PEG). - View Dependent Claims (17)
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21. A method comprising:
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providing a composition including a mineral component and a non-aqueous component having an aqueous replacement characteristic;
inserting an expandable device into a bone;
expanding said expandable device to create a cavity or space within the bone; and
delivering said composition to the bone through a delivery device, wherein said non-aqueous component is replaced with aqueous body fluid, thereby hardening said composition to provide a hardened bone substitute material.
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Specification