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Biomolecular sensors and detection methods utilizing photoinduced charge separation

  • US 20050255515A1
  • Filed: 06/14/2005
  • Published: 11/17/2005
  • Est. Priority Date: 03/28/2002
  • Status: Abandoned Application
First Claim
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1. A method of detecting a target biomolecule in a sample, comprising:

  • (a) labeling said target biomolecule with a photoinducible charge-separation moiety to produce a labeled target molecule;

    (b) contacting said labeled target biomolecule with a substrate bound to a probe biomolecule for said target;

    (c) contacting said substrate with an electron acceptor that is detectably reduced by said charge-separation moiety if said charge-separation moiety is photoinduced; and

    (d) photoinducing said charge-separation moiety provide a detectable reduced electron acceptor; and

    (e) detecting said detectable reduced electron acceptor.

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