Device for renal protection

• US 20050256441A1
• Filed: 04/26/2004
• Published: 11/17/2005
• Est. Priority Date: 04/26/2004
• Status: Abandoned Application

• Current Assignee: Hadasit Medical Research Services & Development Ltd (Hadassah, The Women's Zionist Organization of America, Inc.)
• Original Assignee: Hadasit Medical Research Services & Development Ltd (Hadassah, The Women's Zionist Organization of America, Inc.)
• Inventors: Meerkin, David, Lotan, Chaim, Weiss, Teddy
• Application Number:
  US10/831,227
• Publication Number:
  US 20050256441A1
• Time in Patent Office: Days
• US Class Current: 604/4.10
• CPC Class Codes: A61M 1/3613 Reperfusion, e.g. of the coronary vessels, e.g. retroperfusion
• CPC Class Codes: A61M 1/3621 Extra-corporeal blood circuits single-needle circuits A61M1/30
• CPC Class Codes: A61M 1/3679 by absorption A61M1/3675 takes precedence
• CPC Class Codes: A61M 2025/1052 for temporarily occluding a vessel for isolating a sector
• CPC Class Codes: A61M 2205/32 with radio-opaque indicia
• CPC Class Codes: A61M 25/0017 specially adapted for long-term hygiene care, e.g. urethral or indwelling catheters to prevent infections
• CPC Class Codes: A61M 25/007 Side holes, e.g. their profiles or arrangements; Provisions to keep side holes unblocked

Abstract

A device and method is provided for protecting the renal system from contrast dyes injected into the circulatory system during procedures such as angiograms and angioplasty. The device includes a catheter having a draining portion and an occluding portion. The device is inserted into the coronary sinus at a predetermined time, the occluding portion is inflated, and the contrast-injected blood is diverted. This blood may be reintroduced into the coronary arteries several times.

Claims

1. A device for draining blood from a bodily vessel, the device comprising:

a draining portion having a proximal end and a distal end, the draining portion comprises an outlet on said distal end and a tubing leading from said outlet to said proximal end; and

an occluding portion, wherein the occluding portion is positioned proximal to said outlet, said occluding portion in fluid communication with a port for injecting a gas to inflate said occluding portion.

2. The device of claim 1, wherein said occluding portion has compliant properties.

3. The device of claim 1, wherein said tubing leads past said proximal end and outside of said device.

4. The device of claim 1, wherein said occluding portion is an inflatable balloon.

5. The device of claim 1, wherein said gas is carbon dioxide.

6. The device of claim 1, wherein said gas is helium.

7. The device of claim 1, wherein said occluding portion is a compliant-type balloon.

8. A method for protecting the renal system from contrast dyes within the circulatory system, the method comprising:

providing a catheter having a draining portion comprising a proximal end and a distal end, an outlet on said distal end and a tubing leading from said outlet to said proximal end and an occluding portion, wherein the occluding portion is positioned proximal to said outlet;

inserting said distal end of said draining portion into a predetermined location within a circulatory system;

introducing an angiogram catheter into a coronary artery;

injecting a contrast material into said coronary artery, thus providing contrast-injected blood;

determining a moment of entry of said contrast-injected blood into said predetermined location;

activating said occluding portion so as to block drainage of said contrast-injected blood beyond said predetermined location;

diverting said contrast-injected blood into said outlet and through said tubing;

determining an end of entry of said contrast-injected blood into said predetermined location; and

deactivating said occluding portion so as to allow blood flow past said predetermined location to resume, wherein said deactivating occurs less than one second after said activating.

9. The method of claim 8, wherein said predetermined location is a coronary sinus location.

10. The method of claim 9, wherein said coronary sinus location is a coronary sinus orifice.

11. The method of claim 9, wherein said coronary sinus location is a branch of the coronary sinus.

12. The method of claim 8, wherein said determining is done by timing.

13. The method of claim 8, wherein said determining is done by examining an electrocardiogram.

14. The method of claim 8, wherein said determining is done by visualization.

15. The method of claim 8, wherein said activating includes introducing a gas into said occluding portion, and wherein said occluding portion is expandable and said gas causes said occluding portion to expand.

16. The method of claim 15, wherein said gas is carbon dioxide.

17. The method of claim 15, wherein said gas is helium.

18. The method of claim 15, wherein the occluding portion is an umbrella device and wherein said activating is done by expanding said umbrella device.

19. The method of claim 15, wherein said inserting is done via the superior vena cava.

20. The method of claim 8, further comprising:

collecting said contrast-injected blood outside a body; and

reinjecting said contrast-injected blood into the coronary arteries via said angiogram catheter.

21. The method of claim 20, further comprising:

repeating said reinjecting and said diverting and said collecting until viewing of the coronary arteries is completed; and

removing said catheter from the circulatory system.

22. The method of claim 8, further comprising:

collecting said contrast-injected blood outside a body;

separating said contrast material from said blood; and

reinjecting said blood into the circulatory system.

23. A method for protecting the renal system from contrast dyes within the circulatory system, the method comprising:

providing a catheter having a draining portion comprising a proximal end and a distal end, an outlet on said distal end and a tubing leading from said outlet to said proximal end;

inserting said distal end of said draining portion into a coronary sinus location within a circulatory system;

introducing an angiogram catheter into a coronary artery;

injecting a contrast material into said coronary artery, thus providing contrast-injected blood;

diverting said contrast-injected blood into said outlet and through said tubing;

collecting said contrast-injected blood outside a body;

reinjecting said contrast-injected blood into the coronary arteries via said angiogram catheter;

repeating said reinjecting and said diverting and said collecting until viewing of the coronary arteries is completed; and

removing said draining portion from said coronary sinus location.

24. The method of claim 23, wherein said catheter further comprises an occluding portion, and further comprising

determining a moment of entry of said contrast-injected blood into said coronary sinus location;

activating said occluding portion so as to block drainage of said contrast-injected blood beyond said predetermined location;

determining an end of entry of said contrast-injected blood into said predetermined location; and

deactivating said occluding portion so as to allow blood flow past said predetermined location to resume.

25. The method of claim 23, wherein said coronary sinus location is a coronary sinus orifice.

26. The method of claim 23, wherein said coronary sinus location is a branch of the coronary sinus.

27. The method of claim 24, wherein said determining is done by timing.

28. The method of claim 24, wherein said determining is done by examining an electrocardiogram.

29. The method of claim 24, wherein said determining is done by visualization.

30. The method of claim 24, wherein said activating includes introducing a fluid into said occluding portion, and wherein said occluding portion is expandable and said fluid causes said occluding portion to expand.

31. The method of claim 30, wherein said fluid is a liquid.

32. The method of claim 30, wherein said fluid is a gas.

33. The method of claim 24, wherein said occluding portion is a compliant balloon and wherein said activating occurs rapidly by inflation of said compliant balloon.

34. The method of claim 24, wherein the occluding portion is an umbrella device and wherein said activating is done by expanding said umbrella device.

35. The method of claim 23, wherein said inserting is done via the superior vena cava.

36. A method for protecting the renal system from contrast dyes within the circulatory system, the method comprising:

providing a catheter having a draining portion comprising a proximal end and a distal end, an outlet on said distal end and a tubing leading from said outlet to said proximal end;

inserting said distal end of said draining portion through the superior vena cava into a coronary sinus location within a circulatory system;

introducing an angiogram catheter into a coronary artery;

injecting a contrast material into said coronary artery, thus providing contrast-injected blood;

diverting said contrast-injected blood into said outlet and through said tubing; and

removing said draining portion from said coronary sinus location.

37. The method of claim 36, wherein said catheter further comprises an occluding portion, and further comprising

determining a moment of entry of said contrast-injected blood into said coronary sinus location;

activating said occluding portion so as to block drainage of said contrast-injected blood beyond said predetermined location;

determining an end of entry of said contrast-injected blood into said predetermined location; and

deactivating said occluding portion so as to allow blood flow past said predetermined location to resume.

38. The method of claim 36, wherein said coronary sinus location is a coronary sinus orifice.

39. The method of claim 36, wherein said coronary sinus location is a branch of the coronary sinus.

40. The method of claim 37, wherein said determining is done by timing.

41. The method of claim 37, wherein said determining is done by examining an electrocardiogram.

42. The method of claim 37, wherein said determining is done by visualization.

43. The method of claim 37, wherein said activating includes introducing a gas into said occluding portion, and wherein said occluding portion is expandable and said gas causes said occluding portion to expand.

44. The method of claim 43, wherein said gas is carbon dioxide.

45. The method of claim 43, wherein said gas is helium.

46. The method of claim 37, wherein said occluding portion is a compliant balloon and wherein said activating occurs rapidly by inflation of said compliant balloon.

47. The method of claim 37, wherein the occluding portion is an umbrella device and wherein said activating is done by expanding said umbrella device.

48. The method of claim 36, further comprising:

collecting said contrast-injected blood outside a body; and

reinjecting said contrast-injected blood into the coronary arteries via said angiogram catheter.

49. The method of claim 48, further comprising:

repeating said reinjecting and said diverting and said collecting until viewing of the coronary arteries is completed; and

removing said catheter from the circulatory system.

50. The method of claim 36, further comprising:

collecting said contrast-injected blood outside a body;

separating said contrast material from said blood; and

reinjecting said blood into the circulatory system.