Methods for treating dermatological and other health-related conditions in a patient

• US 20050261367A1
• Filed: 03/28/2005
• Published: 11/24/2005
• Est. Priority Date: 03/29/2004
• Status: Abandoned Application

• Current Assignee: Howard Murad
• Original Assignee: Howard Murad
• Inventors: Murad, Howard
• Application Number:
  US11/090,567
• Publication Number:
  US 20050261367A1
• Time in Patent Office: Days
• US Class Current: 514/492
• CPC Class Codes: A61K 2800/92 Oral administration
• CPC Class Codes: A61K 31/198 Alpha-amino acids, e.g. alanine or edetic acid [EDTA] betaine A61K31/205; proline A61K31/401; tryptophan A61K31/405; histidine A61K31/4172; peptides not degraded to individual amino acids A61K38/00
• CPC Class Codes: A61K 31/28 Compounds containing heavy metals
• CPC Class Codes: A61K 8/022 Powders; Compacted Powders
• CPC Class Codes: A61Q 19/00 Preparations for care of the skin
• CPC Class Codes: A61Q 19/007 Preparations for dry skin
• CPC Class Codes: A61Q 19/06 for countering cellulitis
• CPC Class Codes: A61Q 19/08 Anti-ageing preparations
• CPC Class Codes: A61Q 5/00 Preparations for care of the hair
• CPC Class Codes: A61Q 5/006 Antidandruff preparations
• CPC Class Codes: A61Q 5/12 Preparations containing hair conditioners

Abstract

A method is provided for treating a dermatological condition in a patient. The method includes (a) measuring the intracellular water content of the patient to provide an initial intracellular water content measurement; (b) administering to the patient at least one active agent; (c) re-measuring the intracellular water content of the patient to provide a post-treatment intracellular water content measurement; and (d) repeating steps (b) and (c) until the post-treatment intracellular water content measurement is greater than the initial intracellular water content measurement. A method is also provided for treating other health-related conditions in a patient.

Claims

1. A method for treating a dermatological condition in a patient comprising:

(a) measuring the intracellular water content of the patient to provide an initial intracellular water content measurement;

(b) administering to the patient at least one active agent;

(c) re-measuring the intracellular water content of the patient to provide a post-treatment intracellular water content measurement; and

(d) repeating steps (b) and (c) until the post-treatment intracellular water content measurement is greater than the initial intracellular water content measurement.

2. The method of claim 1, wherein the at least one active agent is administered orally.

3. The method of claim 1, wherein the at least one active agent is administered topically.

4. The method of claim 1, wherein the post-treatment intracellular water content measurement is at least about 0.25 percentage units greater than the initial intracellular water content measurement.

5. The method of claim 1, wherein the post-treatment intracellular water content measurement is at least about 1 percentage unit greater than the initial intracellular water content measurement.

6. The method of claim 1, wherein the post-treatment intracellular water content measurement is at least about 5 percentage units greater than the initial intracellular water content measurement.

7. The method of claim 1, wherein the post-treatment intracellular water content measurement is at least about 10 percentage units greater than the initial intracellular water content measurement.

8. The method of claim 1, wherein the active agent is administered to the patient at least daily for at least about 1 day before re-measuring the patient'"'"'s intracellular water content.

9. The method of claim 1, wherein the active agent is administered to the patient at least daily for at least about 7 days before re-measuring the patient'"'"'s intracellular water content.

10. The method of claim 1, wherein the active agent is administered to the patient at least daily for at least 14 days before re-measuring the patient'"'"'s intracellular water content.

11. The method of claim 1, wherein the active agent is administered to the patient at least daily for at least about 28 days before re-measuring the patient'"'"'s intracellular water content.

12. The method of claim 1, further comprising taking a photographic image of the patient'"'"'s skin before obtaining the initial intracellular water content measurement to provide a first photograph of the dermatological condition and taking a photograph after obtaining the post-treatment intracellular water content measurement to record a second photograph of the dermatological condition and comparing the first photograph and the second photograph to evaluate whether a further increase in the patient'"'"'s intracellular water content is needed to improve the dermatological condition.

13. The method of claim 1, further comprising:

(a1) measuring the extracellular water content of the patient before administering the at least one active agent to the patient to provide an initial extracellular water content measurement and (c1) then re-measuring the extracellular water content after administering the at least one active agent to the patient to provide a post-treatment extracellular water content measurement; and

(d1) repeating steps (a1) and (c1) until the post-treatment extracellular water content measurement is less than the initial extracellular water content measurement.

14. The method of claim 1, further comprising:

(a2) measuring the basal metabolic rate of the patient before administering the at least one active agent to the patient to provide an initial basal metabolic rate measurement and (c2) then re-measuring the basal metabolic rate after administering the at least one active agent to the patient to provide a post-treatment basal metabolic rate measurement; and

(d2) repeating steps (a2) and (c2) until the post-treatment basal metabolic rate measurement is greater than the initial basal metabolic rate measurement.

15. The method of claim 1, further comprising:

(a1) measuring the extracellular water content of the patient before administering the at least one active agent to the patient to provide an initial extracellular water content measurement and (a2) measuring the basal metabolic rate of the patient before administering the at least one active agent to the patient to provide an initial basal metabolic rate measurement;

then (c1) re-measuring the extracellular water content after administering the at least one active agent to the patient to provide a post-treatment extracellular water content measurement and (c2) re-measuring the basal metabolic rate after administering the at least one active agent to the patient to provide a post-treatment basal metabolic rate measurement; and

(d1) repeating steps (a1) and (c1) until the post-treatment extracellular water content measurement is less than the extracellular water content measurement and (d2) repeating steps (a2) and (c2) until the post-treatment basal metabolic rate measurement is greater than the initial basal metabolic rate measurement.

16. The method of claim 1, wherein the at least one active agent comprises an active agent selected from the group consisting of at least one moisturizing agent, a primary antioxidant, an amino acid, at least one amino acid, and at least one transition metal.