Noninvasive determination of alcohol in tissue
First Claim
1. An apparatus for non-invasive determination of an attribute of human tissue by quantitative near infrared spectroscopy comprising:
- an illumination subsystem;
a tissue sampling subsystem, in optical communication with the illumination subsystem;
a spectrometer subsystem in optical communication with the tissue sampling subsystem, said spectrometer subsystem including a spectrometer;
a data acquisition subsystem including a detector which receives an output from the spectrometer subsystem and converts said output to a communicable representation, said data acquisition subsystem including means for modifying said communicable representation and producing an analyzable representation thereof; and
a processing subsystem for receiving said analyzable representation and further including means for determining the attribute from said analyzable representation.
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Abstract
An apparatus and method for non-invasive determination of attributes of human tissue by quantitative infrared spectroscopy. The system includes subsystems optimized to contend with the complexities of the tissue spectrum, high signal-to-noise ratio and photometric accuracy requirements, tissue sampling errors, calibration maintenance problems, and calibration transfer problems. The subsystems include an illumination subsystem, a tissue sampling subsystem, a spectrometer subsystem, a data acquisition subsystem, and a processing subsystem. The invention is applicable, as examples, to determining the concentration or change of concentration of alcohol in human tissue.
84 Citations
31 Claims
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1. An apparatus for non-invasive determination of an attribute of human tissue by quantitative near infrared spectroscopy comprising:
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an illumination subsystem;
a tissue sampling subsystem, in optical communication with the illumination subsystem;
a spectrometer subsystem in optical communication with the tissue sampling subsystem, said spectrometer subsystem including a spectrometer;
a data acquisition subsystem including a detector which receives an output from the spectrometer subsystem and converts said output to a communicable representation, said data acquisition subsystem including means for modifying said communicable representation and producing an analyzable representation thereof; and
a processing subsystem for receiving said analyzable representation and further including means for determining the attribute from said analyzable representation. - View Dependent Claims (2, 3, 4, 5, 6, 7, 8, 9, 10, 11, 12, 13, 14, 15, 16, 17, 18, 19, 20, 21, 22, 23, 24, 25, 26, 27, 28, 30)
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29. An apparatus for non-invasive determination of an attribute of human tissue by quantitative near infrared spectroscopy comprising:
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an illumination subsystem;
a spectrometer subsystem in optical communication with the illumination subsystem, said spectrometer subsystem including a spectrometer;
a tissue sampling subsystem, in optical communication with the spectrometer subsystem;
a data acquisition subsystem including a detector which receives an output from the tissue sampling subsystem and converts said output to a communicable representation, said data acquisition subsystem including means for modifying said communicable representation and producing an analyzable representation thereof; and
a processing subsystem for receiving said analyzable representation and further including means for determining the attribute from said analyzable representation. - View Dependent Claims (31)
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Specification