Blood testing and therapeutic compound delivery system

• US 20050261561A1
• Filed: 05/20/2005
• Published: 11/24/2005
• Est. Priority Date: 05/24/2004
• Status: Abandoned Application

• Current Assignee: Christopher W. Jones
• Original Assignee: Christopher W. Jones
• Inventors: Jones, Christopher W., Tracy, Allen, Embry, Carl
• Application Number:
  US11/134,221
• Publication Number:
  US 20050261561A1
• Time in Patent Office: Days
• US Class Current: 600/315
• CPC Class Codes: A61B 5/14532 for measuring glucose, e.g. by tissue impedance measurement
• CPC Class Codes: A61B 5/1459 invasive, e.g. introduced into the body by a catheter A61B5/1464 takes precedence
• CPC Class Codes: A61B 5/6848 Needles
• CPC Class Codes: A61M 2230/201 Glucose concentration
• CPC Class Codes: A61M 5/1723 using feedback of body parameters, e.g. blood-sugar, pressure measurement of body parameters A61B5/00

Abstract

A system and method are provided for determining intravenous blood levels of a target compound contained in a blood vessel of a patient. The method includes the operation of detecting concentrations of the target compound within a patient'"'"'s blood using a sensor device configured to optically test blood at a location within the blood vessel. Another operation is calculating a measured amount of a therapeutic compound to administer into the patient'"'"'s bloodstream based on the concentrations of the target compound in the blood. The measured amount of therapeutic compound may then be pumped through the catheter into the patient'"'"'s blood.

Claims

1. A method for determining intravenous blood levels of a target compound contained in a blood vessel of a patient, comprising the steps of:

detecting concentrations of the target compound within a patient'"'"'s blood using a sensor device configured to optically test blood at a location within the blood vessel;

calculating a measured amount of a therapeutic compound to administer into the patient'"'"'s bloodstream based on concentrations of the target compound detected in the blood; and

pumping a measured amount of therapeutic compound through a catheter into the patient'"'"'s blood.

2. A method as in claim 1, wherein the step of detecting concentrations further comprises the step of detecting glucose concentrations within a patient'"'"'s bloodstream using the sensor device.

3. A method as in claim 2, further comprising the step of pumping a measured amount of insulin into the patient'"'"'s blood vessel in order to maintain blood glucose within a specified range.

4. A method as in claim 1, wherein the step of providing a sensor device further comprises the step of using an optical fiber supported by the catheter, wherein the optical fiber extends into the blood vessel.

5. A method as in claim 4, an electronic sensor for receiving optical radiation returned by the optical fiber.

6. A device for responsively delivering therapeutic compounds into a bloodstream, comprising:

an intravenous catheter inserted into a blood vessel of a patient;

a detector in optical communication with blood within the blood vessel via the intravenous catheter, the detector being configured to detect at least one target compound in the patient'"'"'s bloodstream;

a processing unit configured to receive detector measurements from the detector and calculate a concentration of the target compound in the patent'"'"'s bloodstream; and

a pump configured to deliver an amount of a therapeutic compound directly into the bloodstream as calculated by the processing unit.

7. A device as in claim 6, wherein the detector is an optical sensor using at least one optical fiber.

8. A device as in claim 7, wherein optical radiation is delivered into the bloodstream using at least one optical fiber.

9. A device as in claim 7, wherein at least a portion of the optical fiber is covered with anti-coagulant.

10. A device as in claim 6, wherein the detector can receive optical radiation to detect concentrations of a target compound in the patient'"'"'s bloodstream.

11. A device as in claim 6, wherein the target compound is glucose and the therapeutic compound is insulin.

12. A device as in claim 6, wherein the intravenous catheter has a plurality of lumens.

13. A device as in claim 6, wherein the detector further includes a negative pressure pump to withdraw blood from the blood vessel and enable optical testing of the blood.

14. A device as in claim 13, further comprising a filter to separate serum from the blood to enable the serum to be subjected to optical testing.

15. A devices as in claim 6, wherein the calculation unit receives detector information in electrical form or optical form.

16. A device for responsively delivering therapeutic compounds into a bloodstream, comprising:

an intravenous catheter inserted into a blood vessel of a patient;

an optical fiber, supported by the intravenous catheter, the optical fiber being configured to deliver optical energy into the blood vessel;

an optical sensor coupled to the optical fiber and configured to receive optical backscatter radiation via the optical fiber in order to detect at least one target compound in the patient'"'"'s bloodstream;

a processing unit configured to receive optical sensor measurements and to calculate the concentration of the target compound in the patent'"'"'s bloodstream; and

a pump configured to deliver an amount of a therapeutic compound directly into the bloodstream as calculated by the processing unit.

17. A device as in claim 16, wherein the optical sensor further comprises a separate fiber optic cable configured to receive optical information from the target compound.

18. A device as in claim 16, wherein the optical fiber extends a distance from the intravenous catheter into the blood vessel.

19. A device as in claim 16, wherein at least a portion of the optical fiber is covered with anti-coagulant.

20. A device as in claim 16, further comprising a housing, including:

a laser source for generating optical radiation;

a receiver diode configured to sense optical radiation; and

a container for insulin that is in communication with the pump.

21. A device as in claim 16, further comprising an audible and visible alarm to notify personnel of problem situations selected from the group comprising:

low blood sugar concentrations, high blood sugar concentrations, obstructed flow of fluid, inappropriate pump operation.