Devices and methods for protecting against distal embolisms
First Claim
1. An endovascular intervention method comprising:
- creating a temporary capillary block in vasculature of at least a portion of a patient'"'"'s organ downstream from a site for an endovascular intervention, the capillary block essentially blocking blood flow through capillaries in the portion of the patient'"'"'s organ; and
performing the endovascular intervention.
1 Assignment
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Accused Products
Abstract
The invention disclosed herein provides endovascular intervention methods that entail creating a temporary capillary block in the vasculature of at least a portion of a patient'"'"'s organ, such as a hemisphere of the patient'"'"'s brain, the capillary block essentially blocking blood flow through capillaries in the portion of the patient'"'"'s organ, and performing the endovascular intervention. Distal embolism protection devices are also disclosed that include a blood pump and at least one of a centrifuge element, a dialysis element, a cooling element, and a filtration element. The blood pump is generally capable of drawing blood from a patient'"'"'s vein, circulating the blood through each of the elements so that a characteristic of a blood component may be manipulated therewith, and perfusing the modified blood into a patient'"'"'s artery. A capillary block is thereby created in the vasculature of at least a portion of a patient'"'"'s organ with manipulated blood components.
25 Citations
24 Claims
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1. An endovascular intervention method comprising:
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creating a temporary capillary block in vasculature of at least a portion of a patient'"'"'s organ downstream from a site for an endovascular intervention, the capillary block essentially blocking blood flow through capillaries in the portion of the patient'"'"'s organ; and
performing the endovascular intervention. - View Dependent Claims (2, 3, 4, 5, 6, 7, 8, 9, 10, 11, 12, 13, 14, 15)
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16. An endovascular intervention method comprising:
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creating a temporary capillary block in vasculature of a hemisphere of a patient'"'"'s brain with erythrocytes having modified characteristics, erythrocyte characteristics modified by at least one of increasing erythrocyte size and decreasing erythrocyte cell membrane permeability; and
performing the endovascular intervention.
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17. An endovascular intervention method comprising,
drawing blood from a patient; -
manipulating at least one characteristic of erythrocytes suspended in the drawn blood that affects the ability of blood to circulate through vasculature of a patient'"'"'s brain'"'"'s; and
perfusing the blood having the manipulated suspended component into the patient at a carotid artery upstream of a hemisphere of the patient'"'"'s brain targeted for the capillary block, the capillary block created with the manipulated erythrocytes.
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18. A distal embolism protection device comprising a blood pump and at least one element connected to the pump, the element selected from the group of elements consisting of:
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a centrifuge element;
a dialysis element;
a cooling element; and
a filtration element, the blood pump capable of drawing blood from a patient'"'"'s vein, circulating the blood through each of the elements therewith manipulating at least one characteristic of a blood component that affects an ability of blood to circulate through a patient'"'"'s vasculature, and perfusing the modified blood into a patient'"'"'s artery, a capillary block created in vasculature of at least a portion of a patient'"'"'s organ with the manipulated blood components. - View Dependent Claims (19, 20, 21, 22)
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23. A distal embolism protection device comprising a blood pump and at least two elements connected to the pump, the elements selected from the group of elements consisting of:
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a centrifuge element;
a dialysis element;
a cooling element; and
a filtration element, the blood pump capable of drawing blood from a patient'"'"'s vein, circulating the blood through each of the elements therewith manipulating at least one characteristic of erythrocytes that effects an ability of blood to circulate through a patient'"'"'s vasculature, and perfusing the modified blood into a patient'"'"'s carotid artery, a capillary block created in vasculature of a hemisphere of a patient'"'"'s brain with manipulated blood erythrocytes.
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24. A distal embolism protection device comprising a blood pump connected to at least one means for creating a temporary capillary block in vasculature of at least a portion of a patient'"'"'s organ, the temporary capillary block created by manipulating at least one characteristic of a blood component that affects an ability of blood to circulate through the patient'"'"'s vasculature.
Specification