System and method for automated fluid monitoring

• US 20050261743A1
• Filed: 05/19/2004
• Published: 11/24/2005
• Est. Priority Date: 05/19/2004
• Status: Abandoned Application

• Current Assignee: Pacesetter Incorporated (Abbott Laboratories Incorporated)
• Original Assignee: Pacesetter Incorporated (Abbott Laboratories Incorporated)
• Inventors: Kroll, Mark W.
• Application Number:
  US10/850,589
• Publication Number:
  US 20050261743A1
• Time in Patent Office: Days
• US Class Current: 607/8
• CPC Class Codes: A61B 2562/0219 Inertial sensors, e.g. accelerometers, gyroscopes, tilt switches
• CPC Class Codes: A61B 5/0538 invasively, e.g. using a catheter
• CPC Class Codes: A61B 5/7264 Classification of physiological signals or data, e.g. using neural networks, statistical classifiers, expert systems or fuzzy systems neural networks per se G06N3/00; expert systems per se G06N5/00
• CPC Class Codes: A61N 1/3621 for treating or preventing abnormally high heart rate
• CPC Class Codes: A61N 1/3627 for treating a mechanical deficiency of the heart, e.g. congestive heart failure or cardiomyopathy
• CPC Class Codes: A61N 1/36521 the parameter being derived from measurement of an electrical impedance

Abstract

An implantable cardiac device and method monitors a patient'"'"'s body impedance so as to diagnose medical problems, such as fluid balance problems in congestive heart failure patients. The device monitors the patient'"'"'s position and determines an appropriate time for collecting body impedance data when the patient is in repose. The device then obtains a series of measurements of thoracic impedance by transmitting a signal on at least one lead, which may be a standard pacemaker lead, and sensing a signal received at a different point. The series of measurements are combined to obtain desired representations of thoracic impedance. In an embodiment, impedance is represented by an extracellular water (ECW) resistance value and an intracellular water (ICW) resistance value determined using a Cole calculation method.

Claims

1. A method of operating an implantable cardiac device (ICD) to monitor a patient, the method comprising:

monitoring a position of the patient and making a determination of when the patient assumes a predetermined repose position for at least a predetermined period of time;

initiating a plurality of measurements of thoracic impedance after making said determination that the patient is in said predetermined repose position;

obtaining said plurality of measurements of thoracic impedance by transmitting a signal on at least one ICD lead and sensing a received signal at a point separated from said ICD lead; and

using said measurements to calculate at least one quantity related to thoracic impedance.

2. The method of claim 1, further comprising using said quantity related to thoracic impedance to diagnose said patient.

3. The method of claim 1, wherein a frequency of said signal transmitted on said ICD lead is varied over said plurality of measurements.

4. The method of claim 3, wherein said frequency measured in kilohertz varies during said plurality of measurements between a single digit and three digits of magnitude.

5. The method of claim 4, further comprising sequentially varying said frequency in a sweep between approximately 5 kHz and approximately 500 kHz while taking said plurality of measurements.

6. The method of claim 5, further comprising conducting a plurality of said sweeps and averaging the results.

7. The method of claim 1, wherein said at least one ICD lead comprises a ventricular pacemaker lead ring electrode.

8. The method of claim 1, wherein said at least one ICD lead comprises an axial pacemaker lead ring electrode.

9. The method of claim 8, wherein said at least one ICD lead comprises a ventricular pacemaker lead ring electrode connected in parallel to said axial pacemaker lead ring electrode.

10. The method of claim 1, wherein said received signal is sensed at an axial tip pacemaker lead.

11. The method of claim 1, wherein said received signal is sensed at a ventricular tip pacemaker lead.

12. The method of claim 11, wherein said received signal is sensed from a parallel connection of an axial tip pacemaker lead and said ventricular tip pacemaker lead.

13. The method of claim 1, further comprising calculating an extracellular water (ECW) resistance value and an intracellular water (ICW) resistance value based on said measurements of thoracic impedance.

14. The method of claim 13, wherein said ECW and ICW values are determined using a Cole-Cole calculation method.

15. The method of claim 2, wherein said quantity used to diagnose said patient is transmitted to an external device via telemetry.

16. The method of claim 15, wherein said quantity used to diagnose said patient is measured repeatedly over time and stored to provide trend data for said quantity.

17. A system for monitoring a patient using an implantable cardiac device (ICD), comprising:

monitoring means for sensing a position of the patient and making a determination of when the patient assumes a predetermined repose position for at least a predetermined period of time;

control means for initiating a plurality of measurements of thoracic impedance after making said determination that the patient is in said predetermined repose position;

impedance measuring means for obtaining said plurality of measurements of thoracic impedance by transmitting a signal on at least one ICD lead and sensing a received signal at a point separated from said ICD lead; and

processing means for calculating, using said measurements, at least one quantity related to thoracic impedance.

18. The system of claim 17, further comprising diagnostic indication means for providing information useful in diagnosing the patient, using said quantity related to thoracic impedance.

19. The system of claim 17, wherein said impedance measuring means further comprises frequency varying means for varying a frequency of said signal transmitted on said ICD lead over said plurality of measurements.

20. The system of claim 19, wherein said frequency varying means varies the frequency during said plurality of measurements between a single digit and three digits of magnitude, measured in kilohertz.

21. The system of claim 19, wherein said frequency varying means sequentially varies said frequency in a sweep between approximately 5 kHz and approximately 500 kHz during said plurality of measurements.

22. The system of claim 21, further comprising averaging means for collecting data from a plurality of said sweeps and averaging the results.

23. The system of claim 17, wherein said at least one ICD lead comprises a ventricular pacemaker lead ring electrode.

24. The system of claim 17, wherein said at least one ICD lead comprises an axial pacemaker lead ring electrode.

25. The system of claim 24, wherein said at least one ICD lead comprises a ventricular pacemaker lead ring electrode connected in parallel to said axial pacemaker lead ring electrode.

26. The system of claim 17, wherein said impedance measuring means senses said received signal at an axial tip pacemaker lead.

27. The system of claim 17, wherein said impedance measuring means senses said received signal at a ventricular tip pacemaker lead.

28. The system of claim 27, wherein said impedance measuring means sense said received signal from a parallel connection of an axial tip pacemaker lead and said ventricular tip pacemaker lead.

29. The system of claim 17, further comprising calculating means for calculating an extracellular water (ECW) resistance value and an intracellular water (ICW) resistance value based on said measurements of thoracic impedance.

30. The system of claim 29, wherein said ECW and ICW values are determined using a Cole-Cole calculation method.

31. The system of claim 17, further comprising telemetry means for transmitting said quantity used to diagnose said patient to an external device via telemetry.

32. The system of claim 31, further comprising trend monitoring means for storing, over time, repeated measurements of said quantity used to diagnose said patient over time, to provide trend data for said quantity.